In vitro assessment of non-irritant microemulsified voriconazole hydrogel system

Research was aimed on microemulsion-based hydrogel for voriconazole. Oleic acid and isopropyl myristate as lipid phases; tween 20: tween 80 as surfactants and PEG600 as cosurfactant were selected to formulate voriconazole microemulsions. The promising microemulsions in terms of zeta potential, pH, v...

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Veröffentlicht in:	Artificial cells, nanomedicine, and biotechnology nanomedicine, and biotechnology, 2017-12, Vol.45 (8), p.1539-1547
Hauptverfasser:	Raju Y, Prasanna, N, Hyndavi, Chowdary V, Harini, Nair, Rajesh S, Basha D, Jamal, N, Tejeswari
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antifungal Agents - chemistry Antifungal Agents - metabolism Antifungal Agents - pharmacology Antifungal Agents - toxicity Diffusion Drug Compounding Drug delivery systems Emulsions Formulations Fungi Fungicides Hydrogels Hydrogels - chemistry Hydrogen-Ion Concentration Materials Testing membrane-transport MIC microemulsion Microemulsions Oleic acid Permeability pH effects Rats Skin - drug effects Solubility Surface-Active Agents - chemistry Viscosity Voriconazole Voriconazole - chemistry Voriconazole - metabolism Voriconazole - pharmacology Voriconazole - toxicity Zeta potential
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