Sustained benefit in rheumatoid arthritis following one course of rituximab : improvements in physical function over 2 years

To evaluate the long-term impact on physical function of a single course of rituximab in rheumatoid factor, seropositive patients with active rheumatoid arthritis (RA) despite ongoing methotrexate treatment. A randomized, controlled trial comparing rituximab alone [1,000 mg intravenously (iv) on day...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2006-12, Vol.45 (12), p.1505-1513
Hauptverfasser:	STRAND, V, BALBIR-GURMAN, A, PAVELKA, K, EMERY, P, LI, N, YIN, M, LEHANE, P. B, AGARWAL, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Murine-Derived Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - physiopathology Biological and medical sciences Cyclophosphamide - therapeutic use Diseases of the osteoarticular system Double-Blind Method Drug Therapy, Combination Female Follow-Up Studies Humans Immunomodulators Immunosuppressive Agents - therapeutic use Inflammatory joint diseases Male Medical sciences Methotrexate - therapeutic use Middle Aged Pain Measurement Pharmacology. Drug treatments Recovery of Function Rituximab Severity of Illness Index Treatment Outcome
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