The effects of (22S,23S)- and (22R,23R)-3[beta]-hydroxy-22,23-oxido-5[alpha]-ergost-8(14)-en-15-ones on biosynthesis of cholesteryl esters and activity of acyl-CoA:Cholesterol acyl transferase in Hep G2 cells

Novel synthetic oxysterols (22S,23S)-3β-hydroxy-22,23-oxido-5α-ergost-8(14)-en-15-one (I) and (22R,23R)-3β-hydroxy-22,23-oxido-5α-ergost-8(14)-en-15-one (II) influenced biosynthesis of cholesteryl esters from [14C]acetate (85% and 180% of control at 5 μM concentration) in the human hepatoma Hep G2 c...

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Veröffentlicht in:	Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry Biomedical chemistry, 2008-12, Vol.2 (4), p.406
Hauptverfasser:	Mehtiev, A R, Kozlova, N I, Skripnik, V V, Misharin, A Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biosynthesis Cells Cholesterol Enzymes
Online-Zugang:	Volltext
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