Gold Nanoparticles as Assisted Matrices for the Detection of Biomolecules in a High-Salt Solution through Laser Desorption/Ionization Mass Spectrometry

Citrate-capped gold nanoparticles (AuNPs) serve as matrices for the determination of biomolecules in a high-salt solution through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). In the case of using 2,5-dihydroxybenzoic acid (2,5-DHB) as a matrix, the sig...

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Veröffentlicht in:	Journal of the American Society for Mass Spectrometry 2009-05, Vol.20 (5), p.875-882
Hauptverfasser:	Wu, Hsin-Pin, Yu, Cheng-Ju, Lin, Chin-Yu, Lin, Yen-Hsiu, Tseng, Wei-Lung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adducts Alkali metals Analytical biochemistry: general aspects, technics, instrumentation Analytical Chemistry Analytical, structural and metabolic biochemistry Angiotensin I - analysis Bioinformatics Biological and medical sciences Biomolecules Biotechnology Carbohydrates Carbohydrates - analysis Chemistry Chemistry and Materials Science Citric Acid - chemistry Creatinine Creatinine - urine Desorption Dihydroxybenzoic acid Female Fundamental and applied biological sciences. Psychology G(M1) Ganglioside - analysis Gangliosides - analysis Gentisates - chemistry Glucose - analysis Gold Gold - chemistry Humans Hydrocortisone - analysis Indoles - analysis Investigative techniques, diagnostic techniques (general aspects) Ionization Ions Lasers Linear Models Mass spectrometry Medical sciences Metal Nanoparticles - chemistry Miscellaneous. Technology Nanoparticles Organic Chemistry Osmolar Concentration Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Proteomics Scientific imaging Sensitivity and Specificity Signal processing Sodium Chloride - chemistry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Spectroscopy Steroids Steroids - analysis Urea - urine Uric acid Uric Acid - urine Urine
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