EFFICACY AND SAFETY OF LEFLUNOMIDE ALONE AND IN COMBINATION WITH METHOTREXATE IN THE TREATMENT OF REFRACTORY RHEUMATOID ARTHRITIS

BACKGROUND: Rheumatoid arthritis patients who develop refractoriness are left with no alternatives other than leflunomide and costly biological response modifiers. Leflunomide, though effective, was associated with adverse events and has not been extensively studied in the Indian population. AIMS: D...

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