Rehabilitating the addicted brain with transcranial magnetic stimulation
Transcranial magnetic stimulation (TMS) is emerging as a potential broad-spectrum therapy for addiction. In this Opinion article, Diana and colleagues discuss the neural foundations of TMS and discuss possible mechanisms underlying the beneficial effects observed in people with addictions. Substance...
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| Veröffentlicht in: | Nature reviews. Neuroscience 2017-11, Vol.18 (11), p.685-693 |
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| creator | Diana, Marco Raij, Tommi Melis, Miriam Nummenmaa, Aapo Leggio, Lorenzo Bonci, Antonello |
| description | Transcranial magnetic stimulation (TMS) is emerging as a potential broad-spectrum therapy for addiction. In this Opinion article, Diana and colleagues discuss the neural foundations of TMS and discuss possible mechanisms underlying the beneficial effects observed in people with addictions.
Substance use disorders (SUDs) are one of the leading causes of morbidity and mortality worldwide. In spite of considerable advances in understanding the neural underpinnings of SUDs, therapeutic options remain limited. Recent studies have highlighted the potential of transcranial magnetic stimulation (TMS) as an innovative, safe and cost-effective treatment for some SUDs. Repetitive TMS (rTMS) influences neural activity in the short and long term by mechanisms involving neuroplasticity both locally, under the stimulating coil, and at the network level, throughout the brain. The long-term neurophysiological changes induced by rTMS have the potential to affect behaviours relating to drug craving, intake and relapse. Here, we review TMS mechanisms and evidence that rTMS is opening new avenues in addiction treatments. |
| doi_str_mv | 10.1038/nrn.2017.113 |
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Neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Diana, Marco</au><au>Raij, Tommi</au><au>Melis, Miriam</au><au>Nummenmaa, Aapo</au><au>Leggio, Lorenzo</au><au>Bonci, Antonello</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rehabilitating the addicted brain with transcranial magnetic stimulation</atitle><jtitle>Nature reviews. Neuroscience</jtitle><stitle>Nat Rev Neurosci</stitle><addtitle>Nat Rev Neurosci</addtitle><date>2017-11-01</date><risdate>2017</risdate><volume>18</volume><issue>11</issue><spage>685</spage><epage>693</epage><pages>685-693</pages><issn>1471-003X</issn><eissn>1471-0048</eissn><eissn>1469-3178</eissn><abstract>Transcranial magnetic stimulation (TMS) is emerging as a potential broad-spectrum therapy for addiction. In this Opinion article, Diana and colleagues discuss the neural foundations of TMS and discuss possible mechanisms underlying the beneficial effects observed in people with addictions.
Substance use disorders (SUDs) are one of the leading causes of morbidity and mortality worldwide. In spite of considerable advances in understanding the neural underpinnings of SUDs, therapeutic options remain limited. Recent studies have highlighted the potential of transcranial magnetic stimulation (TMS) as an innovative, safe and cost-effective treatment for some SUDs. Repetitive TMS (rTMS) influences neural activity in the short and long term by mechanisms involving neuroplasticity both locally, under the stimulating coil, and at the network level, throughout the brain. The long-term neurophysiological changes induced by rTMS have the potential to affect behaviours relating to drug craving, intake and relapse. Here, we review TMS mechanisms and evidence that rTMS is opening new avenues in addiction treatments.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>28951609</pmid><doi>10.1038/nrn.2017.113</doi><tpages>9</tpages></addata></record> |
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| subjects | 631/1647/2204/1453/2105 631/1647/245/1627 631/378/1689/5 631/378/3920 64/60 9/74 Addictions Animal Genetics and Genomics Behavior, Addictive - diagnosis Behavior, Addictive - physiopathology Behavior, Addictive - therapy Behavioral Sciences Biological Techniques Biomedicine Brain - physiology Care and treatment Drug addiction Humans Magnetic brain stimulation Magnetic fields Methods Morbidity Neurobiology Neuronal Plasticity - physiology Neuroplasticity Neurosciences opinion-2 Patient outcomes Stimulation Substance-related disorders Substance-Related Disorders - physiopathology Substance-Related Disorders - therapy Transcranial magnetic stimulation Transcranial Magnetic Stimulation - methods Treatment Outcome |
| title | Rehabilitating the addicted brain with transcranial magnetic stimulation |
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