NF-[kappa]B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

The activation of NF-[kappa]B by receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families requires the TRAF family of adaptor proteins. Receptor oligomerization causes the recruitment of TRAFs to the receptor complex, followed by the activation of a kinas...

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Veröffentlicht in:The EMBO journal 1999-12, Vol.18 (23), p.6694
Hauptverfasser: Pomerantz, Joel L, Baltimore, David
Format: Artikel
Sprache:eng
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