SCFHOS ubiquitin ligase mediates the ligand-induced down-regulation of the interferon- receptor
Down-regulation of activated signaling receptors in response to their ligands plays a key role in restricting the extent and duration of the signaling. Mechanisms underlying down-regulation of the type I interferon receptor consisting of IFNAR1 and IFNAR2 subunits remain largely unknown. Here we sho...
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| Veröffentlicht in: | The EMBO journal 2003-10, Vol.22 (20), p.5480-5490 |
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| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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