Altered aggregation properties of mutant [gamma]-crystallins cause inherited cataract

Protein inclusions are associated with a diverse group of human diseases ranging from localized neurological disorders through to systemic non-neuropathic diseases. Here, we present evidence that the formation of intranuclear inclusions is a key event in cataract formation involving altered [gamma]-...

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Veröffentlicht in:	The EMBO journal 2002-11, Vol.21 (22), p.6005
Hauptverfasser:	Sandilands, Aileen, Hutcheson, Aileen M, Long, Heather A, Prescott, Alan R, Vrensen, Gijs, Loster, Jana, Klopp, Norman, Lutz, Raimund B, Graw, Jochen, Masaki, Shigeo, Dobson, Christopher M, MacPhee, Cait E, Quinlan, Roy A
Format:	Artikel
Sprache:	eng
Schlagworte:	Cataracts
Online-Zugang:	Volltext
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