Psychopharmacological Neuroprotection in Neurodegenerative Disease: Assessing the Preclinical Data

This manuscript reviews the preclinical in vitro, ex vivo, and nonhuman in vivo effects of psychopharmacological agents in clinical use on cell physiology with a view toward identifying agents with neuroprotective properties in neurodegenerative disease. These agents are routinely used in the sympto...

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Veröffentlicht in:	The journal of neuropsychiatry and clinical neurosciences 2010-01, Vol.22 (1), p.8-18
Hauptverfasser:	Lauterbach, Edward C, Victoroff, Jeff, Coburn, Kerry L, Shillcutt, Samuel D, Doonan, Suzanne M, Mendez, Mario F
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer Disease - metabolism Amyloid beta-Peptides - metabolism Antioxidants - therapeutic use Antipsychotic Agents - pharmacology Antipsychotic Agents - therapeutic use Benzodiazepines - pharmacology Benzodiazepines - therapeutic use Benzothiazoles - pharmacology Benzothiazoles - therapeutic use Biological and medical sciences Brain - drug effects Brain - physiopathology Clonazepam - pharmacology Clonazepam - therapeutic use Desipramine - pharmacology Desipramine - therapeutic use Dibenzothiazepines - pharmacology Dibenzothiazepines - therapeutic use Dopamine Agonists - pharmacology Dopamine Agonists - therapeutic use Humans Lithium Carbonate - pharmacology Lithium Carbonate - therapeutic use Maprotiline - pharmacology Maprotiline - therapeutic use Medical sciences Melatonin - therapeutic use Neurodegenerative Diseases - drug therapy Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - physiopathology Neuropharmacology Neuroprotective agent Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Parkinson Disease - drug therapy Parkinson Disease - metabolism Pharmacology. Drug treatments Quetiapine Fumarate Serotonin Uptake Inhibitors - pharmacology Serotonin Uptake Inhibitors - therapeutic use Valproic Acid - pharmacology Valproic Acid - therapeutic use
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