Inhibitory effect of safranal and crocin, two principle compounds of Crocus sativus, on fibrillation of lysozyme

A key feature in more than twenty amyloid-related diseases is the aggregation of intra-and/or extracellular misfolded proteins as amyloid fibrils. Therefore, preventing or reversing amyloid aggregation by using of small molecules is considered as useful approaches to the treatment of these diseases....

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Veröffentlicht in:Journal of the Iranian Chemical Society 2017-11, Vol.14 (11), p.2407-2416
Hauptverfasser: Joloudar, Tahereh Naderi, Saboury, Ali Akbar, Shasaltaneh, Marzieh Dehghan, Bahramikia, Seifollah, Ebrahimi, Mohammad Ali, Ghasemi, Atiyeh
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Sprache:eng
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