Characterizing Gene and Protein Crosstalks in Subjects at Risk of Developing Alzheimer’s Disease: A New Computational Approach

Alzheimer’s disease (AD) is a major public health threat; however, despite decades of research, the disease mechanisms are not completely understood, and there is a significant dearth of predictive biomarkers. The availability of systems biology approaches has opened new avenues for understanding di...

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Veröffentlicht in:	Processes 2017-09, Vol.5 (4), p.47
Hauptverfasser:	Padmanabhan, Kanchana, Nudelman, Kelly, Harenberg, Steve, Bello, Gonzalo, Sohn, Dongwha, Shpanskaya, Katie, Tiwari Dikshit, Priyanka, Yerramsetty, Pallavi, Tanzi, Rudolph, Saykin, Andrew, Petrella, Jeffrey, Doraiswamy, P., Samatova, Nagiza, Alzheimer’s Disease Neuroimaging Initiative
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Apolipoprotein E Biomarkers Cognitive ability Computation Computer applications Crosstalk Dementia disorders Encyclopedias Gene polymorphism Genomes Neurodegenerative diseases Polymorphism Public health Single-nucleotide polymorphism
Online-Zugang:	Volltext
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