Selective Inhibition of NF-κB and Surfactant Therapy in Experimental Meconium-Induced Lung Injury

Meconium aspiration syndrome (MAS) in newborns is characterized mainly by respiratory failure due to surfactant dysfunction and inflammation. Previous meta-analyses did not prove any effect of exogenous surfactant treatment nor glucocorticoid administration on final outcome of children with MAS desp...

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Veröffentlicht in:	Physiological research 2017-01, Vol.66, p.S227-S236
Hauptverfasser:	KOPINCOVA, J., MIKOLKA, P., KOLOMAZNIK, M., KOSUTOVA, P., CALKOVSKA, A., MOKRA, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Apoptosis Bronchus Caspase Caspase-3 Children Cytokines Design of experiments Glucocorticoids Inflammation Interleukin 6 Kinases MAP kinase Mechanical ventilation Meconium Neonates NF-κB protein Oxygen Oxygenation Peptides Rabbits Respiratory failure Rodents Surfactants
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