Differential regulation of the cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1 by phosphorylation directed by the cyclin encoded by Murine Herpesvirus 68

Members of the [gamma]2-herpesvirus family encode cyclin-like proteins that have the ability to deregulate mammalian cell cycle control. Here we report the key features of the viral cyclin encoded by Murine Herpesvirus 68, M cyclin. M cyclin preferentially associated with and activated cdk2; the M c...

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Veröffentlicht in:	Experimental cell research 2008-01, Vol.314 (1), p.204-212
Hauptverfasser:	Yarmishyn, Aliaksandr, Child, Emma S., Elphick, Lucy M., Mann, David J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell cycle Cellular biology Herpes viruses Kinases
Online-Zugang:	Volltext
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