Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities

The biological complexity of NGF action is achieved by binding two distinct neurotrophin receptors, TrkA and p75NTR. While several reports have provided lines of evidence on the interaction between TrkA and p75NTR at the plasma membrane, much fewer data are available on the consequence of such an in...

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Veröffentlicht in:	Experimental cell research 2007-08, Vol.313 (14), p.2980-2992
Hauptverfasser:	DIOLAITI, D, BERNARDONI, R, TRAZZI, S, PAPA, A, PORRO, A, BONO, F, HERBERT, J, PERINI, G, DELLAVALLE, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular biology Molecular biology Neurons Signal transduction
Online-Zugang:	Volltext
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