Direct and Stereospecific [3+2] Synthesis of Pyrrolidines from Simple Unactivated Alkenes

Pyrrolidines are important heterocyclic compounds with endless applications in organic synthesis, metal catalysis, and organocatalysis. Their potential as ligands for first‐row transition‐metal catalysts inspired a new method to access complex poly‐heterocyclic pyrrolidines in one step from available materials. This fundamental step forward is based on the discovery of an essential organoaluminum promoter that engages unactivated and electron‐rich olefins in intermolecular [3+2] cycloadditions. Trimethylaluminium vermittelt [3+2]‐Cycloadditionen von Azomethin‐Yliden mit nichtelektrophilen Olefinen. Durch diese Reaktion lassen sich leicht zugängliche Ausgangsstoffe stereoselektiv zu Gerüsten für das Design neuer polarer mehrzähniger Liganden kombinieren.