Porous membranes of the polycaprolactone (PCL) containing calcium silicate fibers for guided bone regeneration

•Development of the porous PLC membranes containing calcium silicate fibers (CaSiO3).•A high porous microstructure was obtained by the controlled humidity method.•Changes in physical, chemical and thermal properties of the PCL membranes were achieved. Porous membranes of polycaprolactone containing calcium silicate fibers for guided bone regeneration were prepared by a controlled humidity method. The results indicated the development of the novel membrane microstructure with porosity and surface roughness increased. The pore size varied between 4.76–14.28µm and the roughness increase 72.8% compared with control. These characteristics can provide a better interaction with the biological medium combined to the osteoconduction properties of the calcium silicate fibers and biocompatibility of the PCL. Therefore, the porous PCL/CaSiO3 membranes are promising biomaterial for guided bone regeneration.