Safety of Polyethylene Terephthalate Food Containers Evaluated by HPLC, Migration Test, and Estimated Daily Intake
A comparative high‐pressure liquid chromatography (HPLC) analysis of monomers, terephthalic acid (TPA), isophthalic acid (IPA), and dimethyl terephthalate (DMT) from polyethylene terephthalate (PET) food containers was conducted. Monomer linearities and sensitivities were calibrated between establis...
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| Veröffentlicht in: | Journal of food science 2008-08, Vol.73 (6), p.T83-T89 |
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| container_issue | 6 |
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| container_title | Journal of food science |
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| creator | Park, H.-J. Lee, Y.J. Kim, M.-R. Kim, K.M. |
| description | A comparative high‐pressure liquid chromatography (HPLC) analysis of monomers, terephthalic acid (TPA), isophthalic acid (IPA), and dimethyl terephthalate (DMT) from polyethylene terephthalate (PET) food containers was conducted. Monomer linearities and sensitivities were calibrated between established and novel HPLC analyses. Safety of PET containers was evaluated with newly established detection methods for TPA, IPA, and DMT. Migration of the 3 monomers into food simulants (water, 4% acetic acid, 20% alcohol, and n‐heptane) from 56 PET containers collected from open markets was monitored. Migrated monomers were not detected over 0.1 ppm of detection limit. The corresponding estimated daily intake was measured to confirm the safety of these publicly available PET containers and to permit comparison to the specific migration limit of the European Union. The estimated daily intake of 3 monomers migrating from PET was 0.0384 mg/kg each. This represented only 0.6% of the European Union's specific migration limit, confirming the safety of the examined containers. |
| doi_str_mv | 10.1111/j.1750-3841.2008.00840.x |
| format | Article |
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Monomer linearities and sensitivities were calibrated between established and novel HPLC analyses. Safety of PET containers was evaluated with newly established detection methods for TPA, IPA, and DMT. Migration of the 3 monomers into food simulants (water, 4% acetic acid, 20% alcohol, and n‐heptane) from 56 PET containers collected from open markets was monitored. Migrated monomers were not detected over 0.1 ppm of detection limit. The corresponding estimated daily intake was measured to confirm the safety of these publicly available PET containers and to permit comparison to the specific migration limit of the European Union. The estimated daily intake of 3 monomers migrating from PET was 0.0384 mg/kg each. This represented only 0.6% of the European Union's specific migration limit, confirming the safety of the examined containers.</description><identifier>ISSN: 0022-1147</identifier><identifier>EISSN: 1750-3841</identifier><identifier>DOI: 10.1111/j.1750-3841.2008.00840.x</identifier><identifier>PMID: 19241591</identifier><identifier>CODEN: JFDSAZ</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Biological and medical sciences ; Chromatography ; Chromatography, High Pressure Liquid - methods ; Comparative analysis ; Consumer Product Safety ; Containers ; Equipment Reuse ; estimated daily intake ; Food Contamination - analysis ; Food industries ; Food Packaging - methods ; Food science ; Fundamental and applied biological sciences. Psychology ; General aspects ; Humans ; Hygiene and safety ; isophthalic acid ; Migration ; migration test ; Polyethylene terephthalate ; Polyethylene Terephthalates - analysis ; Polyethylene Terephthalates - chemistry ; Polyethylene Terephthalates - toxicity ; Safety ; terephthalic acid</subject><ispartof>Journal of food science, 2008-08, Vol.73 (6), p.T83-T89</ispartof><rights>2008 Institute of Food Technologists</rights><rights>2008 INIST-CNRS</rights><rights>Copyright Institute of Food Technologists Aug 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5280-28ac3b0a4cef89953d3d0d5d57f4a61da9c340a59c06eadcb9e36c9d88e079363</citedby><cites>FETCH-LOGICAL-c5280-28ac3b0a4cef89953d3d0d5d57f4a61da9c340a59c06eadcb9e36c9d88e079363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1750-3841.2008.00840.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1750-3841.2008.00840.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20597492$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19241591$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Park, H.-J.</creatorcontrib><creatorcontrib>Lee, Y.J.</creatorcontrib><creatorcontrib>Kim, M.-R.</creatorcontrib><creatorcontrib>Kim, K.M.</creatorcontrib><title>Safety of Polyethylene Terephthalate Food Containers Evaluated by HPLC, Migration Test, and Estimated Daily Intake</title><title>Journal of food science</title><addtitle>J Food Sci</addtitle><description>A comparative high‐pressure liquid chromatography (HPLC) analysis of monomers, terephthalic acid (TPA), isophthalic acid (IPA), and dimethyl terephthalate (DMT) from polyethylene terephthalate (PET) food containers was conducted. Monomer linearities and sensitivities were calibrated between established and novel HPLC analyses. Safety of PET containers was evaluated with newly established detection methods for TPA, IPA, and DMT. Migration of the 3 monomers into food simulants (water, 4% acetic acid, 20% alcohol, and n‐heptane) from 56 PET containers collected from open markets was monitored. Migrated monomers were not detected over 0.1 ppm of detection limit. The corresponding estimated daily intake was measured to confirm the safety of these publicly available PET containers and to permit comparison to the specific migration limit of the European Union. The estimated daily intake of 3 monomers migrating from PET was 0.0384 mg/kg each. This represented only 0.6% of the European Union's specific migration limit, confirming the safety of the examined containers.</description><subject>Biological and medical sciences</subject><subject>Chromatography</subject><subject>Chromatography, High Pressure Liquid - methods</subject><subject>Comparative analysis</subject><subject>Consumer Product Safety</subject><subject>Containers</subject><subject>Equipment Reuse</subject><subject>estimated daily intake</subject><subject>Food Contamination - analysis</subject><subject>Food industries</subject><subject>Food Packaging - methods</subject><subject>Food science</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Humans</subject><subject>Hygiene and safety</subject><subject>isophthalic acid</subject><subject>Migration</subject><subject>migration test</subject><subject>Polyethylene terephthalate</subject><subject>Polyethylene Terephthalates - analysis</subject><subject>Polyethylene Terephthalates - chemistry</subject><subject>Polyethylene Terephthalates - toxicity</subject><subject>Safety</subject><subject>terephthalic acid</subject><issn>0022-1147</issn><issn>1750-3841</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtvEzEUhS0EoqHwF5CFxK4z-DUPL1igPNqiFCoS1KV1Y3vIpNOZ1HZo5t_X00RhiyXLtu53jo8OQpiSlMb1ZZPSIiMJLwVNGSFlGrcg6f4VGp0Gr9GIEMYSSkVxht55vyHDm-dv0RmVTNBM0hFyC6hs6HFX4duu6W1Y941tLV5aZ7frsIYGgsWzrjN43LUB6tY6j6d_odnFgcGrHl_dzscX-Kb-4yDUXRulPlxgaA2e-lA_vGATqJseX0eDe_sevamg8fbD8TxHv2fT5fgqmf-8vB5_myc6YyVJWAmarwgIbatSyowbbojJTFZUAnJqQGouCGRSk9yC0Stpea6lKUtLCslzfo4-HXy3rnvcxVBq0-1cG79UVArBiCwGqDxA2nXeO1uprYuZXa8oUUPXaqOGStVQqRq6Vi9dq32Ufjz671YP1vwTHsuNwOcjAF5DUzlode1PHCOZLIRkkft64J7qxvb_HUB9n00W8Rb1yUFf-2D3Jz24e5UXvMjU3Y9LNblZ_JqUS6Lu-DMiW6lJ</recordid><startdate>200808</startdate><enddate>200808</enddate><creator>Park, H.-J.</creator><creator>Lee, Y.J.</creator><creator>Kim, M.-R.</creator><creator>Kim, K.M.</creator><general>Blackwell Publishing Inc</general><general>Institute of Food Technologists</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QR</scope><scope>7ST</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>SOI</scope></search><sort><creationdate>200808</creationdate><title>Safety of Polyethylene Terephthalate Food Containers Evaluated by HPLC, Migration Test, and Estimated Daily Intake</title><author>Park, H.-J. ; Lee, Y.J. ; Kim, M.-R. ; Kim, K.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5280-28ac3b0a4cef89953d3d0d5d57f4a61da9c340a59c06eadcb9e36c9d88e079363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Biological and medical sciences</topic><topic>Chromatography</topic><topic>Chromatography, High Pressure Liquid - methods</topic><topic>Comparative analysis</topic><topic>Consumer Product Safety</topic><topic>Containers</topic><topic>Equipment Reuse</topic><topic>estimated daily intake</topic><topic>Food Contamination - analysis</topic><topic>Food industries</topic><topic>Food Packaging - methods</topic><topic>Food science</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Humans</topic><topic>Hygiene and safety</topic><topic>isophthalic acid</topic><topic>Migration</topic><topic>migration test</topic><topic>Polyethylene terephthalate</topic><topic>Polyethylene Terephthalates - analysis</topic><topic>Polyethylene Terephthalates - chemistry</topic><topic>Polyethylene Terephthalates - toxicity</topic><topic>Safety</topic><topic>terephthalic acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, H.-J.</creatorcontrib><creatorcontrib>Lee, Y.J.</creatorcontrib><creatorcontrib>Kim, M.-R.</creatorcontrib><creatorcontrib>Kim, K.M.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Journal of food science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, H.-J.</au><au>Lee, Y.J.</au><au>Kim, M.-R.</au><au>Kim, K.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Safety of Polyethylene Terephthalate Food Containers Evaluated by HPLC, Migration Test, and Estimated Daily Intake</atitle><jtitle>Journal of food science</jtitle><addtitle>J Food Sci</addtitle><date>2008-08</date><risdate>2008</risdate><volume>73</volume><issue>6</issue><spage>T83</spage><epage>T89</epage><pages>T83-T89</pages><issn>0022-1147</issn><eissn>1750-3841</eissn><coden>JFDSAZ</coden><abstract>A comparative high‐pressure liquid chromatography (HPLC) analysis of monomers, terephthalic acid (TPA), isophthalic acid (IPA), and dimethyl terephthalate (DMT) from polyethylene terephthalate (PET) food containers was conducted. Monomer linearities and sensitivities were calibrated between established and novel HPLC analyses. Safety of PET containers was evaluated with newly established detection methods for TPA, IPA, and DMT. Migration of the 3 monomers into food simulants (water, 4% acetic acid, 20% alcohol, and n‐heptane) from 56 PET containers collected from open markets was monitored. Migrated monomers were not detected over 0.1 ppm of detection limit. The corresponding estimated daily intake was measured to confirm the safety of these publicly available PET containers and to permit comparison to the specific migration limit of the European Union. The estimated daily intake of 3 monomers migrating from PET was 0.0384 mg/kg each. This represented only 0.6% of the European Union's specific migration limit, confirming the safety of the examined containers.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>19241591</pmid><doi>10.1111/j.1750-3841.2008.00840.x</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of food science, 2008-08, Vol.73 (6), p.T83-T89 |
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| subjects | Biological and medical sciences Chromatography Chromatography, High Pressure Liquid - methods Comparative analysis Consumer Product Safety Containers Equipment Reuse estimated daily intake Food Contamination - analysis Food industries Food Packaging - methods Food science Fundamental and applied biological sciences. Psychology General aspects Humans Hygiene and safety isophthalic acid Migration migration test Polyethylene terephthalate Polyethylene Terephthalates - analysis Polyethylene Terephthalates - chemistry Polyethylene Terephthalates - toxicity Safety terephthalic acid |
| title | Safety of Polyethylene Terephthalate Food Containers Evaluated by HPLC, Migration Test, and Estimated Daily Intake |
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