In Vitro Iron Bioavailability and Antioxidant Activity of Raisins
Iron bioavailabilities and antioxidant activities of 3 generic raisin types‐Golden Thompson, Dipped Thompson, and Sun‐dried Thompson‐were quantified and compared. Iron bioavailability was assessed with an in vitro digestion/Caco‐2 cell culture model using cell ferritin formation as an index of iron...
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Veröffentlicht in: | Journal of food science 2003-03, Vol.68 (2), p.701-705 |
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description | Iron bioavailabilities and antioxidant activities of 3 generic raisin types‐Golden Thompson, Dipped Thompson, and Sun‐dried Thompson‐were quantified and compared. Iron bioavailability was assessed with an in vitro digestion/Caco‐2 cell culture model using cell ferritin formation as an index of iron bioavailability. Antioxidant activity was determined using the total oxyradical‐scavenging capacity (TOSC) assay. Ferritin formation in Caco‐2 cells was low for all 3 raisin types, indicating low iron bioavailability. Ethylenediaminetetraacetic acid (EDTA) enhanced iron bioavailability from raisins but ascorbic, citric, and tartaric acids showed no effect. Antioxidant activity was significantly higher in Golden Thompson than Dipped Thompson and Sun‐dried Thompson, suggesting that enzymatic browning negatively affected antioxidant activity. |
doi_str_mv | 10.1111/j.1365-2621.2003.tb05735.x |
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Iron bioavailability was assessed with an in vitro digestion/Caco‐2 cell culture model using cell ferritin formation as an index of iron bioavailability. Antioxidant activity was determined using the total oxyradical‐scavenging capacity (TOSC) assay. Ferritin formation in Caco‐2 cells was low for all 3 raisin types, indicating low iron bioavailability. Ethylenediaminetetraacetic acid (EDTA) enhanced iron bioavailability from raisins but ascorbic, citric, and tartaric acids showed no effect. Antioxidant activity was significantly higher in Golden Thompson than Dipped Thompson and Sun‐dried Thompson, suggesting that enzymatic browning negatively affected antioxidant activity.</description><identifier>ISSN: 0022-1147</identifier><identifier>EISSN: 1750-3841</identifier><identifier>DOI: 10.1111/j.1365-2621.2003.tb05735.x</identifier><identifier>CODEN: JFDSAZ</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>antioxidant activity ; Bioavailability ; Caco-2 cell culture ; Food science ; Fruits ; Iron ; raisins</subject><ispartof>Journal of food science, 2003-03, Vol.68 (2), p.701-705</ispartof><rights>Copyright Institute of Food Technologists Mar 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3821-818764d8868aaa3093b7ed512f5a5abff41c084833f6275f8db5f2a9d62526ce3</citedby><cites>FETCH-LOGICAL-c3821-818764d8868aaa3093b7ed512f5a5abff41c084833f6275f8db5f2a9d62526ce3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2621.2003.tb05735.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2621.2003.tb05735.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids></links><search><creatorcontrib>Yeung, C.K.</creatorcontrib><creatorcontrib>Glahn, R.P.</creatorcontrib><creatorcontrib>Wu, X.</creatorcontrib><creatorcontrib>Liu, R.H.</creatorcontrib><creatorcontrib>Miller, D.D.</creatorcontrib><title>In Vitro Iron Bioavailability and Antioxidant Activity of Raisins</title><title>Journal of food science</title><description>Iron bioavailabilities and antioxidant activities of 3 generic raisin types‐Golden Thompson, Dipped Thompson, and Sun‐dried Thompson‐were quantified and compared. Iron bioavailability was assessed with an in vitro digestion/Caco‐2 cell culture model using cell ferritin formation as an index of iron bioavailability. Antioxidant activity was determined using the total oxyradical‐scavenging capacity (TOSC) assay. Ferritin formation in Caco‐2 cells was low for all 3 raisin types, indicating low iron bioavailability. Ethylenediaminetetraacetic acid (EDTA) enhanced iron bioavailability from raisins but ascorbic, citric, and tartaric acids showed no effect. Antioxidant activity was significantly higher in Golden Thompson than Dipped Thompson and Sun‐dried Thompson, suggesting that enzymatic browning negatively affected antioxidant activity.</description><subject>antioxidant activity</subject><subject>Bioavailability</subject><subject>Caco-2 cell culture</subject><subject>Food science</subject><subject>Fruits</subject><subject>Iron</subject><subject>raisins</subject><issn>0022-1147</issn><issn>1750-3841</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNqVkMlOwzAQhi0EEqXwDlHvCV7iJVxQaOnCKrGUo-UslhxCUuy0pG9PolTcmctoNPN_I30ATBAMUFeXRYAIoz5mGAUYQhI0CaSc0KA9AiPEKfSJCNExGEGIsY9QyE_BmXMF7GfCRiBeVd7aNLb2VrauvBtTq50ypUpMaZq9p6rMi6vG1K3JVNV4cdqYXb-otfeijDOVOwcnWpUuvzj0MXif375Nl_7D82I1jR_8lAiMfIEEZ2EmBBNKKQIjkvA8owhrqqhKtA5RCkUoCNEMc6pFllCNVZQxTDFLczIGk4G7sfX3NneNLOqtrbqXEkUhiSDnpDu6Go5SWztncy031nwpu5cIyt6YLGRvTPbGZG9MHozJtgtfD-EfU-b7fyTl3Xz2yiHqCP5AMK7J2z-Csp-SccKp_HhayMf72ZpFcCmX5BcLdoFV</recordid><startdate>200303</startdate><enddate>200303</enddate><creator>Yeung, C.K.</creator><creator>Glahn, R.P.</creator><creator>Wu, X.</creator><creator>Liu, R.H.</creator><creator>Miller, D.D.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QR</scope><scope>7ST</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>SOI</scope></search><sort><creationdate>200303</creationdate><title>In Vitro Iron Bioavailability and Antioxidant Activity of Raisins</title><author>Yeung, C.K. ; Glahn, R.P. ; Wu, X. ; Liu, R.H. ; Miller, D.D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3821-818764d8868aaa3093b7ed512f5a5abff41c084833f6275f8db5f2a9d62526ce3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>antioxidant activity</topic><topic>Bioavailability</topic><topic>Caco-2 cell culture</topic><topic>Food science</topic><topic>Fruits</topic><topic>Iron</topic><topic>raisins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yeung, C.K.</creatorcontrib><creatorcontrib>Glahn, R.P.</creatorcontrib><creatorcontrib>Wu, X.</creatorcontrib><creatorcontrib>Liu, R.H.</creatorcontrib><creatorcontrib>Miller, D.D.</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Journal of food science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yeung, C.K.</au><au>Glahn, R.P.</au><au>Wu, X.</au><au>Liu, R.H.</au><au>Miller, D.D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vitro Iron Bioavailability and Antioxidant Activity of Raisins</atitle><jtitle>Journal of food science</jtitle><date>2003-03</date><risdate>2003</risdate><volume>68</volume><issue>2</issue><spage>701</spage><epage>705</epage><pages>701-705</pages><issn>0022-1147</issn><eissn>1750-3841</eissn><coden>JFDSAZ</coden><abstract>Iron bioavailabilities and antioxidant activities of 3 generic raisin types‐Golden Thompson, Dipped Thompson, and Sun‐dried Thompson‐were quantified and compared. Iron bioavailability was assessed with an in vitro digestion/Caco‐2 cell culture model using cell ferritin formation as an index of iron bioavailability. Antioxidant activity was determined using the total oxyradical‐scavenging capacity (TOSC) assay. Ferritin formation in Caco‐2 cells was low for all 3 raisin types, indicating low iron bioavailability. Ethylenediaminetetraacetic acid (EDTA) enhanced iron bioavailability from raisins but ascorbic, citric, and tartaric acids showed no effect. Antioxidant activity was significantly higher in Golden Thompson than Dipped Thompson and Sun‐dried Thompson, suggesting that enzymatic browning negatively affected antioxidant activity.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><doi>10.1111/j.1365-2621.2003.tb05735.x</doi><tpages>5</tpages></addata></record> |
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subjects | antioxidant activity Bioavailability Caco-2 cell culture Food science Fruits Iron raisins |
title | In Vitro Iron Bioavailability and Antioxidant Activity of Raisins |
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