On a multiobjective optimal control of a tumor growth model with immune response and drug therapies

In this paper, we consider a tumor growth mathematical model that includes an immune system and drug therapies. Immuno‐ and chemodrug administration as well as periodic administration of radiation are integrated in the model. We have set an optimal control (OC) problem relative to the model so that...

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Veröffentlicht in:	International transactions in operational research 2018-01, Vol.25 (1), p.269-294
Hauptverfasser:	Rocha, Ana Maria A.C., Costa, M. Fernanda P., Fernandes, Edite M.G.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug therapy Functionals Growth models Immune system multiobjective approach Multiple objective analysis Operations research Optimal control tumor model
Online-Zugang:	Volltext
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