Deletion of AMPK[alpha]1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release

Background and Purpose Perivascular adipose tissue (PVAT) surrounds most blood vessels and secretes numerous active substances, including adiponectin, which produce a net anticontractile effect in healthy individuals. AMPK is a key mediator of cellular energy balance and may mediate the vascular eff...

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Veröffentlicht in:	British journal of pharmacology 2017-10, Vol.174 (20), p.3398
Hauptverfasser:	Almabrouk, Tarek A M, Ugusman, Azizah B, Katwan, Omar J, Salt, Ian P, Kennedy, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Adipose tissue Adipose tissue (brown) Aorta Blood vessels Clonal deletion Endothelium Energy balance Enzyme-linked immunosorbent assay Molecular modelling Rodents Secretion Thorax
Online-Zugang:	Volltext
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