Reactive oxygen species generation is essential for cisplatininduced accelerated senescence in hepatocellular carcinoma

Accelerated senescence is important because this process is involved in tumor suppression and has been induced by many chemotherapeutic agents. The platinum-based chemotherapeutic agent cisplatin displays a wide range of antitumor activities. However, the molecular mechanism of cisplatin-induced acc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Frontiers of medicine 2014-06, Vol.8 (2), p.227-235
Hauptverfasser:	Qu, Kai, Lin, Ting, Wang, Zhixin, Liu, Sinan, Chang, Hulin, Xu, Xinsen, Meng, Fandi, Zhou, Lei, Wei, Jichao, Tai, Minghui, Dong, Yafeng, Liu, Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	HepG2 Liver cancer Medicine Medicine & Public Health p21基因 p53基因 Reactive oxygen species Research Article Senescence SMMC-7721细胞 活性氧清除剂 细胞衰老 聚合酶链式反应 肝癌细胞
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!