Comparison of adverse events following injection of original or generic docetaxel for the treatment of breast cancer

Purpose The approval of injectable generic drugs does not require bioequivalence testing. However, although generic products contain the same level of the active compound, the levels and types of additives present can differ from those used in the original product. Since docetaxel is highly lipophil...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 2017-10, Vol.80 (4), p.841-849
Hauptverfasser:	Tagawa, Nao, Sugiyama, Erika, Tajima, Masataka, Sasaki, Yasutsuna, Nakamura, Seigo, Okuyama, Hiromi, Shimizu, Hisanori, Sato, Vilasinee Hirunpanich, Sasaki, Tadanori, Sato, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Additives Adult Aged Alcohol Alcohols Anticancer properties Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Antineoplastic Agents - chemistry Breast cancer Breast Neoplasms - drug therapy Cancer Cancer Research Drugs Drugs, Generic - administration & dosage Drugs, Generic - adverse effects Drugs, Generic - chemistry Ethanol Excipients - chemistry Feet Female Generic drugs Generic products Hematology Hospitals, University Humans Incidence Injection Japan Lipophilic Logistic Models Medical records Medicine Medicine & Public Health Middle Aged Mucositis Multivariate Analysis Oncology Original Article Pharmacology Pharmacology/Toxicology Physiochemistry Polyethylene glycol Polyethylenes Polyoxyethylene sorbitan monooleate Retrospective Studies Solubility Taxoids - administration & dosage Taxoids - adverse effects Taxoids - chemistry Taxotere Terminology Therapeutic Equivalency Toxicity
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