From medicinal plant extracts to defined chemical compounds targeting the histamine H^sub 4^ receptor: Curcuma longa in the treatment of inflammation

The aim was to evaluate the activity of seven medicinal, anti-inflammatory plants at the hH4R with focus on defined chemical compounds from Curcuma longa. Activities were analyzed with membrane preparations from Sf9 cells, transiently expressing the hH4R, Gαi2 and Gβ1γ2 subunits. From the methanolic...

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Veröffentlicht in:	Inflammation research 2017-10, Vol.66 (10), p.923
Hauptverfasser:	Frank, Annika, Abu-lafi, Saleh, Adawi, Azmi, Schwed, Johannes S, Stark, Holger, Rayan, Anwar
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical compounds Curcumin Elution High-performance liquid chromatography Histamine Inflammation Lead Ligands Liquid chromatography Medicinal plants Methane Plant extracts
Online-Zugang:	Volltext
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