A cluster‐randomized controlled trial evaluating the effects of delaying onset of adolescent substance abuse on cognitive development and addiction following a selective, personality‐targeted intervention programme: the Co‐Venture trial
Aims Substance use and binge drinking during early adolescence are associated with neurocognitive abnormalities, mental health problems and an increased risk for future addiction. The trial aims to evaluate the protective effects of an evidence‐based substance use prevention programme on the onset o...
Gespeichert in:
| Veröffentlicht in: | Addiction (Abingdon, England) England), 2017-10, Vol.112 (10), p.1871-1881 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1881 |
|---|---|
| container_issue | 10 |
| container_start_page | 1871 |
| container_title | Addiction (Abingdon, England) |
| container_volume | 112 |
| creator | O'Leary‐Barrett, Maeve Mâsse, Benoit Pihl, Robert O. Stewart, Sherry H. Séguin, Jean R. Conrod, Patricia J. |
| description | Aims
Substance use and binge drinking during early adolescence are associated with neurocognitive abnormalities, mental health problems and an increased risk for future addiction. The trial aims to evaluate the protective effects of an evidence‐based substance use prevention programme on the onset of alcohol and drug use in adolescence, as well as on cognitive, mental health and addiction outcomes over 5 years.
Design
Thirty‐eight high schools will be recruited, with a final sample of 31 schools assigned to intervention or control conditions (3826 youth). Brief personality‐targeted interventions will be delivered to high‐risk youth attending intervention schools during the first year of the trial. Control school participants will receive no intervention above what is offered to them in the regular curriculum by their respective schools.
Setting
Public/private French and English high schools in Montreal (Canada).
Participants
All grade 7 students (12–13 years old) will be invited to participate. High‐risk youth will be identified as those scoring one standard deviation or more above the school mean on one of the four personality subscales of the Substance Use Risk Profile Scale (40–45% youth).
Measurements
Self‐reported substance use and mental health symptoms and cognitive functioning measured annually throughout 5 years. Primary outcomes are the onset of substance use disorders at 4 years post‐intervention (year 5). Secondary intermediate outcomes are the onset of alcohol and substance use 2 years post‐intervention and neuropsychological functions; namely, the protective effects of substance use prevention on cognitive functions generally, and executive functions and reward sensitivity specifically.
Conclusion
This longitudinal, cluster‐randomized controlled trial will investigate the impact of a brief personality‐targeted intervention program on reducing the onset of addiction 4 years‐post intervention. Results will tease apart the developmental sequences of uptake and growth in substance use and cognitive development in adolescence using developmentally sensitive neuropsychological measures. |
| doi_str_mv | 10.1111/add.13876 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1937292283</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1937292283</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3536-2d3fd958bfd8a82b4d607aeed9a5aa38443d9577d4db6bb2434cca1380d9f5e83</originalsourceid><addsrcrecordid>eNp1kc9u1DAQxi0EokvhwAsgS5wqkdaJnX_cVlsKSJW4ANdoYk8WV0682M5Wy4lH4Bn7CDwBk27hhi-2Zn7zzecZxl7m4jyncwHGnOeyqatHbJXLSmRCKfmYrURblVmRK3HCnsV4I4Som1Y9ZSdFUyolRLtiv9dcuzkmDHc_fwWYjB_tDzRc-ykF7xw9U7DgOO7BzZDstOXpG3IcBtQpcj9wgw4OS9xPEdMSAeMdRo1T4nHuY4JJI4d-jkgMSW8nm-weqXKPzu_GBaTWVGesTpaYgVr720UUeERHrYh_w3cYop_A2XQguwnCFhM5tBP535PKUroLfhtgHPHtvdGNJ_Ir5eaAx688Z08GcBFfPNyn7MvVu8-bD9n1p_cfN-vrTMtSVllh5GDasukH00BT9MpUogZE00IJIBsaMaXr2ijTV31fKKm0BlqDMO1QYiNP2eujLjn6PmNM3Y2fA7mPXd7KumiLopFEnR0pHXyMAYduF-wI4dDlolu229FUuvvtEvvqQXHuRzT_yL_rJODiCNxah4f_K3Xry8uj5B-D0Lnd</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1937292283</pqid></control><display><type>article</type><title>A cluster‐randomized controlled trial evaluating the effects of delaying onset of adolescent substance abuse on cognitive development and addiction following a selective, personality‐targeted intervention programme: the Co‐Venture trial</title><source>MEDLINE</source><source>Wiley Online Library</source><creator>O'Leary‐Barrett, Maeve ; Mâsse, Benoit ; Pihl, Robert O. ; Stewart, Sherry H. ; Séguin, Jean R. ; Conrod, Patricia J.</creator><creatorcontrib>O'Leary‐Barrett, Maeve ; Mâsse, Benoit ; Pihl, Robert O. ; Stewart, Sherry H. ; Séguin, Jean R. ; Conrod, Patricia J.</creatorcontrib><description>Aims
Substance use and binge drinking during early adolescence are associated with neurocognitive abnormalities, mental health problems and an increased risk for future addiction. The trial aims to evaluate the protective effects of an evidence‐based substance use prevention programme on the onset of alcohol and drug use in adolescence, as well as on cognitive, mental health and addiction outcomes over 5 years.
Design
Thirty‐eight high schools will be recruited, with a final sample of 31 schools assigned to intervention or control conditions (3826 youth). Brief personality‐targeted interventions will be delivered to high‐risk youth attending intervention schools during the first year of the trial. Control school participants will receive no intervention above what is offered to them in the regular curriculum by their respective schools.
Setting
Public/private French and English high schools in Montreal (Canada).
Participants
All grade 7 students (12–13 years old) will be invited to participate. High‐risk youth will be identified as those scoring one standard deviation or more above the school mean on one of the four personality subscales of the Substance Use Risk Profile Scale (40–45% youth).
Measurements
Self‐reported substance use and mental health symptoms and cognitive functioning measured annually throughout 5 years. Primary outcomes are the onset of substance use disorders at 4 years post‐intervention (year 5). Secondary intermediate outcomes are the onset of alcohol and substance use 2 years post‐intervention and neuropsychological functions; namely, the protective effects of substance use prevention on cognitive functions generally, and executive functions and reward sensitivity specifically.
Conclusion
This longitudinal, cluster‐randomized controlled trial will investigate the impact of a brief personality‐targeted intervention program on reducing the onset of addiction 4 years‐post intervention. Results will tease apart the developmental sequences of uptake and growth in substance use and cognitive development in adolescence using developmentally sensitive neuropsychological measures.</description><identifier>ISSN: 0965-2140</identifier><identifier>EISSN: 1360-0443</identifier><identifier>DOI: 10.1111/add.13876</identifier><identifier>PMID: 28544009</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Addictions ; Adolescence ; Adolescent ; Adolescent Behavior ; Adolescents ; Age Factors ; Alcohol ; Alcohol use ; Alcoholic beverages ; Behavior, Addictive - prevention & control ; Binge drinking ; Brief interventions ; Canada ; Child ; Child development ; Clinical trials ; Cluster Analysis ; cluster‐randomized controlled trial ; Cognition ; Cognition - drug effects ; Cognitive ability ; Cognitive development ; Cognitive functioning ; Curricula ; Developmental delays ; Deviation ; Drinking behavior ; Drug abuse ; Evidence-based medicine ; Executive function ; Female ; First year ; Follow-Up Studies ; Health problems ; Health Promotion - methods ; Health status ; High risk ; Humans ; Intervention ; intervention program ; Longitudinal Studies ; Male ; Mental disorders ; Mental health ; Personality ; prevention ; Prevention programs ; Program Evaluation - methods ; Randomization ; Reinforcement ; Secondary school students ; Secondary schools ; Sequences ; Slopes ; substance misuse ; Substance use ; Substance use disorder ; Substance-Related Disorders - prevention & control ; Teenagers ; Uptake ; Youth</subject><ispartof>Addiction (Abingdon, England), 2017-10, Vol.112 (10), p.1871-1881</ispartof><rights>2017 Society for the Study of Addiction</rights><rights>2017 Society for the Study of Addiction.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3536-2d3fd958bfd8a82b4d607aeed9a5aa38443d9577d4db6bb2434cca1380d9f5e83</citedby><cites>FETCH-LOGICAL-c3536-2d3fd958bfd8a82b4d607aeed9a5aa38443d9577d4db6bb2434cca1380d9f5e83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fadd.13876$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fadd.13876$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28544009$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>O'Leary‐Barrett, Maeve</creatorcontrib><creatorcontrib>Mâsse, Benoit</creatorcontrib><creatorcontrib>Pihl, Robert O.</creatorcontrib><creatorcontrib>Stewart, Sherry H.</creatorcontrib><creatorcontrib>Séguin, Jean R.</creatorcontrib><creatorcontrib>Conrod, Patricia J.</creatorcontrib><title>A cluster‐randomized controlled trial evaluating the effects of delaying onset of adolescent substance abuse on cognitive development and addiction following a selective, personality‐targeted intervention programme: the Co‐Venture trial</title><title>Addiction (Abingdon, England)</title><addtitle>Addiction</addtitle><description>Aims
Substance use and binge drinking during early adolescence are associated with neurocognitive abnormalities, mental health problems and an increased risk for future addiction. The trial aims to evaluate the protective effects of an evidence‐based substance use prevention programme on the onset of alcohol and drug use in adolescence, as well as on cognitive, mental health and addiction outcomes over 5 years.
Design
Thirty‐eight high schools will be recruited, with a final sample of 31 schools assigned to intervention or control conditions (3826 youth). Brief personality‐targeted interventions will be delivered to high‐risk youth attending intervention schools during the first year of the trial. Control school participants will receive no intervention above what is offered to them in the regular curriculum by their respective schools.
Setting
Public/private French and English high schools in Montreal (Canada).
Participants
All grade 7 students (12–13 years old) will be invited to participate. High‐risk youth will be identified as those scoring one standard deviation or more above the school mean on one of the four personality subscales of the Substance Use Risk Profile Scale (40–45% youth).
Measurements
Self‐reported substance use and mental health symptoms and cognitive functioning measured annually throughout 5 years. Primary outcomes are the onset of substance use disorders at 4 years post‐intervention (year 5). Secondary intermediate outcomes are the onset of alcohol and substance use 2 years post‐intervention and neuropsychological functions; namely, the protective effects of substance use prevention on cognitive functions generally, and executive functions and reward sensitivity specifically.
Conclusion
This longitudinal, cluster‐randomized controlled trial will investigate the impact of a brief personality‐targeted intervention program on reducing the onset of addiction 4 years‐post intervention. Results will tease apart the developmental sequences of uptake and growth in substance use and cognitive development in adolescence using developmentally sensitive neuropsychological measures.</description><subject>Addictions</subject><subject>Adolescence</subject><subject>Adolescent</subject><subject>Adolescent Behavior</subject><subject>Adolescents</subject><subject>Age Factors</subject><subject>Alcohol</subject><subject>Alcohol use</subject><subject>Alcoholic beverages</subject><subject>Behavior, Addictive - prevention & control</subject><subject>Binge drinking</subject><subject>Brief interventions</subject><subject>Canada</subject><subject>Child</subject><subject>Child development</subject><subject>Clinical trials</subject><subject>Cluster Analysis</subject><subject>cluster‐randomized controlled trial</subject><subject>Cognition</subject><subject>Cognition - drug effects</subject><subject>Cognitive ability</subject><subject>Cognitive development</subject><subject>Cognitive functioning</subject><subject>Curricula</subject><subject>Developmental delays</subject><subject>Deviation</subject><subject>Drinking behavior</subject><subject>Drug abuse</subject><subject>Evidence-based medicine</subject><subject>Executive function</subject><subject>Female</subject><subject>First year</subject><subject>Follow-Up Studies</subject><subject>Health problems</subject><subject>Health Promotion - methods</subject><subject>Health status</subject><subject>High risk</subject><subject>Humans</subject><subject>Intervention</subject><subject>intervention program</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Mental disorders</subject><subject>Mental health</subject><subject>Personality</subject><subject>prevention</subject><subject>Prevention programs</subject><subject>Program Evaluation - methods</subject><subject>Randomization</subject><subject>Reinforcement</subject><subject>Secondary school students</subject><subject>Secondary schools</subject><subject>Sequences</subject><subject>Slopes</subject><subject>substance misuse</subject><subject>Substance use</subject><subject>Substance use disorder</subject><subject>Substance-Related Disorders - prevention & control</subject><subject>Teenagers</subject><subject>Uptake</subject><subject>Youth</subject><issn>0965-2140</issn><issn>1360-0443</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc9u1DAQxi0EokvhwAsgS5wqkdaJnX_cVlsKSJW4ANdoYk8WV0682M5Wy4lH4Bn7CDwBk27hhi-2Zn7zzecZxl7m4jyncwHGnOeyqatHbJXLSmRCKfmYrURblVmRK3HCnsV4I4Som1Y9ZSdFUyolRLtiv9dcuzkmDHc_fwWYjB_tDzRc-ykF7xw9U7DgOO7BzZDstOXpG3IcBtQpcj9wgw4OS9xPEdMSAeMdRo1T4nHuY4JJI4d-jkgMSW8nm-weqXKPzu_GBaTWVGesTpaYgVr720UUeERHrYh_w3cYop_A2XQguwnCFhM5tBP535PKUroLfhtgHPHtvdGNJ_Ir5eaAx688Z08GcBFfPNyn7MvVu8-bD9n1p_cfN-vrTMtSVllh5GDasukH00BT9MpUogZE00IJIBsaMaXr2ijTV31fKKm0BlqDMO1QYiNP2eujLjn6PmNM3Y2fA7mPXd7KumiLopFEnR0pHXyMAYduF-wI4dDlolu229FUuvvtEvvqQXHuRzT_yL_rJODiCNxah4f_K3Xry8uj5B-D0Lnd</recordid><startdate>201710</startdate><enddate>201710</enddate><creator>O'Leary‐Barrett, Maeve</creator><creator>Mâsse, Benoit</creator><creator>Pihl, Robert O.</creator><creator>Stewart, Sherry H.</creator><creator>Séguin, Jean R.</creator><creator>Conrod, Patricia J.</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>8BJ</scope><scope>FQK</scope><scope>JBE</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>201710</creationdate><title>A cluster‐randomized controlled trial evaluating the effects of delaying onset of adolescent substance abuse on cognitive development and addiction following a selective, personality‐targeted intervention programme: the Co‐Venture trial</title><author>O'Leary‐Barrett, Maeve ; Mâsse, Benoit ; Pihl, Robert O. ; Stewart, Sherry H. ; Séguin, Jean R. ; Conrod, Patricia J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3536-2d3fd958bfd8a82b4d607aeed9a5aa38443d9577d4db6bb2434cca1380d9f5e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Addictions</topic><topic>Adolescence</topic><topic>Adolescent</topic><topic>Adolescent Behavior</topic><topic>Adolescents</topic><topic>Age Factors</topic><topic>Alcohol</topic><topic>Alcohol use</topic><topic>Alcoholic beverages</topic><topic>Behavior, Addictive - prevention & control</topic><topic>Binge drinking</topic><topic>Brief interventions</topic><topic>Canada</topic><topic>Child</topic><topic>Child development</topic><topic>Clinical trials</topic><topic>Cluster Analysis</topic><topic>cluster‐randomized controlled trial</topic><topic>Cognition</topic><topic>Cognition - drug effects</topic><topic>Cognitive ability</topic><topic>Cognitive development</topic><topic>Cognitive functioning</topic><topic>Curricula</topic><topic>Developmental delays</topic><topic>Deviation</topic><topic>Drinking behavior</topic><topic>Drug abuse</topic><topic>Evidence-based medicine</topic><topic>Executive function</topic><topic>Female</topic><topic>First year</topic><topic>Follow-Up Studies</topic><topic>Health problems</topic><topic>Health Promotion - methods</topic><topic>Health status</topic><topic>High risk</topic><topic>Humans</topic><topic>Intervention</topic><topic>intervention program</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Mental disorders</topic><topic>Mental health</topic><topic>Personality</topic><topic>prevention</topic><topic>Prevention programs</topic><topic>Program Evaluation - methods</topic><topic>Randomization</topic><topic>Reinforcement</topic><topic>Secondary school students</topic><topic>Secondary schools</topic><topic>Sequences</topic><topic>Slopes</topic><topic>substance misuse</topic><topic>Substance use</topic><topic>Substance use disorder</topic><topic>Substance-Related Disorders - prevention & control</topic><topic>Teenagers</topic><topic>Uptake</topic><topic>Youth</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>O'Leary‐Barrett, Maeve</creatorcontrib><creatorcontrib>Mâsse, Benoit</creatorcontrib><creatorcontrib>Pihl, Robert O.</creatorcontrib><creatorcontrib>Stewart, Sherry H.</creatorcontrib><creatorcontrib>Séguin, Jean R.</creatorcontrib><creatorcontrib>Conrod, Patricia J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Addiction (Abingdon, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>O'Leary‐Barrett, Maeve</au><au>Mâsse, Benoit</au><au>Pihl, Robert O.</au><au>Stewart, Sherry H.</au><au>Séguin, Jean R.</au><au>Conrod, Patricia J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A cluster‐randomized controlled trial evaluating the effects of delaying onset of adolescent substance abuse on cognitive development and addiction following a selective, personality‐targeted intervention programme: the Co‐Venture trial</atitle><jtitle>Addiction (Abingdon, England)</jtitle><addtitle>Addiction</addtitle><date>2017-10</date><risdate>2017</risdate><volume>112</volume><issue>10</issue><spage>1871</spage><epage>1881</epage><pages>1871-1881</pages><issn>0965-2140</issn><eissn>1360-0443</eissn><abstract>Aims
Substance use and binge drinking during early adolescence are associated with neurocognitive abnormalities, mental health problems and an increased risk for future addiction. The trial aims to evaluate the protective effects of an evidence‐based substance use prevention programme on the onset of alcohol and drug use in adolescence, as well as on cognitive, mental health and addiction outcomes over 5 years.
Design
Thirty‐eight high schools will be recruited, with a final sample of 31 schools assigned to intervention or control conditions (3826 youth). Brief personality‐targeted interventions will be delivered to high‐risk youth attending intervention schools during the first year of the trial. Control school participants will receive no intervention above what is offered to them in the regular curriculum by their respective schools.
Setting
Public/private French and English high schools in Montreal (Canada).
Participants
All grade 7 students (12–13 years old) will be invited to participate. High‐risk youth will be identified as those scoring one standard deviation or more above the school mean on one of the four personality subscales of the Substance Use Risk Profile Scale (40–45% youth).
Measurements
Self‐reported substance use and mental health symptoms and cognitive functioning measured annually throughout 5 years. Primary outcomes are the onset of substance use disorders at 4 years post‐intervention (year 5). Secondary intermediate outcomes are the onset of alcohol and substance use 2 years post‐intervention and neuropsychological functions; namely, the protective effects of substance use prevention on cognitive functions generally, and executive functions and reward sensitivity specifically.
Conclusion
This longitudinal, cluster‐randomized controlled trial will investigate the impact of a brief personality‐targeted intervention program on reducing the onset of addiction 4 years‐post intervention. Results will tease apart the developmental sequences of uptake and growth in substance use and cognitive development in adolescence using developmentally sensitive neuropsychological measures.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>28544009</pmid><doi>10.1111/add.13876</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0965-2140 |
| ispartof | Addiction (Abingdon, England), 2017-10, Vol.112 (10), p.1871-1881 |
| issn | 0965-2140 1360-0443 |
| language | eng |
| recordid | cdi_proquest_journals_1937292283 |
| source | MEDLINE; Wiley Online Library |
| subjects | Addictions Adolescence Adolescent Adolescent Behavior Adolescents Age Factors Alcohol Alcohol use Alcoholic beverages Behavior, Addictive - prevention & control Binge drinking Brief interventions Canada Child Child development Clinical trials Cluster Analysis cluster‐randomized controlled trial Cognition Cognition - drug effects Cognitive ability Cognitive development Cognitive functioning Curricula Developmental delays Deviation Drinking behavior Drug abuse Evidence-based medicine Executive function Female First year Follow-Up Studies Health problems Health Promotion - methods Health status High risk Humans Intervention intervention program Longitudinal Studies Male Mental disorders Mental health Personality prevention Prevention programs Program Evaluation - methods Randomization Reinforcement Secondary school students Secondary schools Sequences Slopes substance misuse Substance use Substance use disorder Substance-Related Disorders - prevention & control Teenagers Uptake Youth |
| title | A cluster‐randomized controlled trial evaluating the effects of delaying onset of adolescent substance abuse on cognitive development and addiction following a selective, personality‐targeted intervention programme: the Co‐Venture trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T11%3A52%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20cluster%E2%80%90randomized%20controlled%20trial%20evaluating%20the%20effects%20of%20delaying%20onset%20of%20adolescent%20substance%20abuse%20on%20cognitive%20development%20and%20addiction%20following%20a%20selective,%20personality%E2%80%90targeted%20intervention%20programme:%20the%20Co%E2%80%90Venture%20trial&rft.jtitle=Addiction%20(Abingdon,%20England)&rft.au=O'Leary%E2%80%90Barrett,%20Maeve&rft.date=2017-10&rft.volume=112&rft.issue=10&rft.spage=1871&rft.epage=1881&rft.pages=1871-1881&rft.issn=0965-2140&rft.eissn=1360-0443&rft_id=info:doi/10.1111/add.13876&rft_dat=%3Cproquest_cross%3E1937292283%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1937292283&rft_id=info:pmid/28544009&rfr_iscdi=true |