Tetraspanin 1 is involved in survival, proliferation and carcinogenesis of pancreatic cancer

Pancreatic cancer (PCC) is one of the most difficult cancers to treat and the 10th leading cause of cancer-related death in worldwide. Studies have demonstrated that the tetraspanin 1 (Tspan1) is overexpressed in various cancers and may be a potential therapeutic strategy for the treatment of differ...

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Veröffentlicht in:	Oncology reports 2015-12, Vol.34 (6), p.3068-3076
Hauptverfasser:	HOU, FENG-QIANG, LEI, XI-FENG, YAO, JIAN-LONG, WANG, YI-JIN, ZHANG, WEI
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - genetics Cancer therapies Carcinogenesis - genetics Cell cycle Cell growth Cell Line, Tumor Cell Proliferation - genetics Cell Survival - genetics Development and progression Ethics Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Health aspects Humans invasion Medical prognosis Membrane proteins Metastasis migration Motility Pancreatic cancer Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Patient outcomes proliferation Properties Proteins RNA, Small Interfering - genetics small interference RNA tetraspanin 1 Tetraspanins - biosynthesis Tetraspanins - genetics Tumors
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