Loss of the metastasis suppressor gene KiSS1 is associated with lymph node metastasis and poor prognosis in human colorectal cancer

Cancer research is currently focused on blocking the metastatic process at its early steps. Some particularly attractive targets are metastasis suppressor genes, which control cancer cell dissemination. The aim of this study was to clarify the relationship between the expression of KiSS1, a metastas...

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Veröffentlicht in:	Oncology reports 2013-09, Vol.30 (3), p.1449-1454
Hauptverfasser:	OKUGAWA, YOSHINAGA, INOUE, YASUHIRO, TANAKA, KOJI, TOIYAMA, YUJI, SHIMURA, TADANOBU, OKIGAMI, MASATO, KAWAMOTO, AYA, HIRO, JUNICHIRO, SAIGUSA, SUSUMU, MOHRI, YASUHIKO, UCHIDA, KEIICHI, KUSUNOKI, MASATO
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - secondary Adolescent Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Breast cancer Cancer therapies Child Colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Confidence intervals Esophagus Female Follow-Up Studies Gene expression Humans Immunoenzyme Techniques KiSS1 Kisspeptins - genetics Kisspeptins - metabolism Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - secondary Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - secondary lymph node metastasis Lymphatic Metastasis Lymphatic system Male Medical prognosis Metastasis Middle Aged Multivariate analysis Neoplasm Invasiveness Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Staging NMR Nuclear magnetic resonance Pathogenesis Peritoneal Neoplasms - genetics Peritoneal Neoplasms - metabolism Peritoneal Neoplasms - secondary Prognosis Prospective Studies Proteins Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Software Statistical analysis Surgery Survival Rate Tumors Young Adult
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