Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes

Non-alcoholic fatty liver disease (NAFLD) is characterized by the hepatic manifestation of metabolic syndrome and is the leading cause of chronic liver disease. Steatohepatitis plays a critical role in the process resulting in liver fibrosis and cirrhosis. Puerarin is a herbal product widely used in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular medicine 2015-03, Vol.35 (3), p.803-809
Hauptverfasser:	KANG, OK-HWA, KIM, SUNG-BAE, MUN, SU-HYUN, SEO, YUN-SOO, HWANG, HYEONG-CHIL, LEE, YOUNG-MI, LEE, HO-SEOB, KANG, DAE-GIL, KWON, DONG-YEUL
Format:	Artikel
Sprache:	eng
Schlagworte:	adenosine 5′-monophosphate-activated protein kinase AMP-Activated Protein Kinases - metabolism Care and treatment Cell culture Cytotoxicity Enzymes Fatty acids Fatty liver Fatty Liver - drug therapy Fatty Liver - genetics Fatty Liver - metabolism Fatty Liver - pathology Gene Expression Regulation - drug effects Genetic aspects Health aspects Hep G2 Cells hepatic lipogenesis Hepatocytes - drug effects Hepatocytes - metabolism Homeostasis Humans Isoflavones Isoflavones - administration & dosage Isoflavones - chemistry Isoflavones - pharmacology Kinases lipid accumulation Lipid Metabolism - drug effects Lipids Liver cirrhosis Liver diseases Metabolic syndrome Oleic Acid - pharmacology Oxidation Peroxisomes Phosphorylation Physiological aspects PPAR alpha - genetics PPAR alpha - metabolism Protein expression Proteins puerarin RNA, Messenger - genetics RNA, Messenger - metabolism Rodents Signal Transduction - drug effects Stains & staining Sterols Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!