E2F1 promotes tumor cell invasion and migration through regulating CD147 in prostate cancer

Increased expression of E2F1 has been reported to be associated with tumor growth and cell survival of prostate cancer (PCa). However, its roles and mechanisms on PCa have not been fully elucidated. The present study found that E2F1 overexpression in PCa tissues was significantly associated with hig...

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Veröffentlicht in:	International journal of oncology 2016-04, Vol.48 (4), p.1650-1658
Hauptverfasser:	LIANG, YU-XIANG, LU, JIAN-MING, MO, RU-JUN, HE, HUI-CHAN, XIE, JIAN, JIANG, FU-NENG, LIN, ZHUO-YUAN, CHEN, YAN-RU, WU, YONG-DING, LUO, HONG-WEI, LUO, ZHENG, ZHONG, WEI-DE
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Basigin - genetics Basigin - metabolism Binding Sites biochemical recurrence-free survival Breast cancer Cancer surgery Cancer therapies CD147 Cell cycle Cell Line, Tumor Cell Movement Development and progression E2F1 E2F1 Transcription Factor - chemistry E2F1 Transcription Factor - metabolism Epithelial-Mesenchymal Transition Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Health aspects Humans Laboratory animals Lung cancer Male Medical prognosis Metastasis Mice Neoplasm Grading Neoplasm Invasiveness Prognosis Properties Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Proteins Studies Survival Analysis Transcription factors tumor invasion tumor migration
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