Prevalence and associated survival of high-risk HPV-related adenoid cystic carcinoma of the salivary glands

Adenoid cystic carcinoma (SACC) is a rare malignancy, but a frequent subtype in minor and major salivary glands. The molecular alterations or biomarkers that underlie its development and progression as well as therapy outcomes are poorly characterized. The main study goal was to investigate reliable...

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Veröffentlicht in:	International journal of oncology 2016-08, Vol.49 (2), p.803-811
Hauptverfasser:	Qian, Xu, Kaufmann, Andreas M, Chen, Chao, Tzamalis, Georgios, Hofmann, Veit M, Keilholz, Ulrich, Hummel, Michael, Albers, Andreas E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biological markers Carcinoma, Adenoid Cystic - epidemiology Carcinoma, Adenoid Cystic - genetics Carcinoma, Adenoid Cystic - pathology Carcinoma, Adenoid Cystic - virology Care and treatment Cell cycle Chemotherapy Cyclin-Dependent Kinase Inhibitor p16 - biosynthesis Deoxyribonucleic acid Development and progression Diagnosis Disease-Free Survival DNA Epidermal growth factor epithelial growth factor receptor ErbB Receptors - biosynthesis Female Gene Expression Regulation, Neoplastic Genetic aspects human papilloma virus Human papillomavirus Humans Identification and classification Infections Kaplan-Meier Estimate Ki-67 Ki-67 Antigen - biosynthesis Lymphatic system Male Medical prognosis Metastasis Middle Aged Multivariate analysis Neoplasm Metastasis Oral cancer p15 p53 Papillomaviridae - classification Papillomaviridae - genetics Papillomaviridae - isolation & purification Papillomaviridae - pathogenicity Papillomavirus infections Pathology Patients prevalenve Radiation therapy salivary gland adenoid cystic carcinoma Salivary Gland Neoplasms - epidemiology Salivary Gland Neoplasms - genetics Salivary Gland Neoplasms - pathology Salivary Gland Neoplasms - virology Salivary gland tumors Salivary Glands - pathology Salivary Glands - virology Studies Surgery survival Tumor Suppressor Protein p53 - biosynthesis Tumors
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