Comparative gene expression profiling of ADAMs, MMPs, TIMPs, EMMPRIN, EGF-R and VEGFA in low grade meningioma

MMPs (matrix metalloproteinases), ADAMs (a disintegrin and metalloproteinase) and TIMPs (tissue inhibitors of metalloproteinases) are implicated in invasion and angiogenesis: both are tissue remodeling processes involving regulated proteolysis of the extracellular matrix, growth factors and their re...

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Veröffentlicht in:	International journal of oncology 2016-12, Vol.49 (6), p.2309-2318
Hauptverfasser:	Rooprai, Harcharan K, Martin, Andrew J, King, Andrew, Appadu, Usha D, Jones, Huw, Selway, Richard P, Gullan, Richard W, Pilkington, Geoffrey J
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins - genetics ADAM Proteins - metabolism ADAMs Adult Aged Angiogenesis Apoptosis Basigin - genetics Basigin - metabolism Biopsy Brain cancer Classification Extracellular matrix Extracellular Matrix - metabolism Female Females Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Glioma Growth factors Humans Kinases Male matrix metalloproteases Matrix Metalloproteinases - genetics Matrix Metalloproteinases - metabolism Meningioma - genetics Meningioma - metabolism meningiomas Middle Aged Real-Time Polymerase Chain Reaction Receptor, Epidermal Growth Factor - genetics Receptor, Epidermal Growth Factor - metabolism Tissue Inhibitor of Metalloproteinases - genetics Tissue Inhibitor of Metalloproteinases - metabolism Tumors Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism
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