0463 Occupational intoxication by mercury and neurotoxicity: professional disease
IntroductionMercury is a heavy metal found naturally in the environment. Mercury poisoning of occupational origin is widely identified as occupational disease. The industries where cases have been described are those dedicated to the manufacture of thermometers, barometers, as well as in gold mines...
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| Veröffentlicht in: | Occupational and environmental medicine (London, England) England), 2017-08, Vol.74 (Suppl 1), p.A147 |
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| creator | Inostrosa, Marita Del Pilar Asmat Valdazo, Javier Valdés Robles, Jose Manuel De La Torre Rio, Maria Victoria Casares Del Herrero, Luis Enrrique Alonso |
| description | IntroductionMercury is a heavy metal found naturally in the environment. Mercury poisoning of occupational origin is widely identified as occupational disease. The industries where cases have been described are those dedicated to the manufacture of thermometers, barometers, as well as in gold mines and metal refineries such as zinc.MethodologyThe case of a 30-year-old male, a boilermaker (welder assembler) who is part of one of the teams responsible for replacing the carbon steel tubes of the exchanger through which sulphurous gases circulate with mercury remains is described. The initial symptoms were diarrhoea with mucus and blood and gum inflammation, initially presenting a blood mercury concentration of 475.9mcg/L (NV= |
| doi_str_mv | 10.1136/oemed-2017-104636.384 |
| format | Article |
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Mercury poisoning of occupational origin is widely identified as occupational disease. The industries where cases have been described are those dedicated to the manufacture of thermometers, barometers, as well as in gold mines and metal refineries such as zinc.MethodologyThe case of a 30-year-old male, a boilermaker (welder assembler) who is part of one of the teams responsible for replacing the carbon steel tubes of the exchanger through which sulphurous gases circulate with mercury remains is described. The initial symptoms were diarrhoea with mucus and blood and gum inflammation, initially presenting a blood mercury concentration of 475.9mcg/L (NV=<10 mcg/L) and urine mercury concentration 939mcg/L (NV=<30 Mcg/L) (BAL INSHT <5 mcg/g creatinine), not receiving treatment until after 6 months with DMPS twice seeing a reduction in urinary values from 1830.47 to 7.38 mcg/L. As a clinical result of mercury poisoning he had severe mercurial erethism with dysthymia and aggressive behaviour, as well as a secondary complex visual disorder and a diarrheal syndrome due to secondary autonomic neuropathy.ConclusionThis paper aims to warn about the consequences of prolonged exposure to mercury especially for the central nervous system, as well as early diagnosis and timely treatment. On the other hand, note the importance of adopting an adequate and effective preventive system to protect the health of workers exposed to mercury.</description><identifier>ISSN: 1351-0711</identifier><identifier>EISSN: 1470-7926</identifier><identifier>DOI: 10.1136/oemed-2017-104636.384</identifier><language>eng</language><publisher>London: BMJ Publishing Group LTD</publisher><subject>2,3-Dimercapto-1-propanesulfonic acid ; Aggressive behavior ; Autonomic nervous system ; Barometers ; Blood ; Blood levels ; Boilers ; Central nervous system ; Creatinine ; Diarrhea ; Exposure ; Gold ; Heavy metals ; Intoxication ; Mercury ; Mercury (metal) ; Mucus ; Neuropathy ; Neurotoxicity ; Occupational diseases ; Occupational exposure ; Occupational health ; Poisoning ; Refineries ; Steel tubes ; Thermometers ; Urine ; Zinc</subject><ispartof>Occupational and environmental medicine (London, England), 2017-08, Vol.74 (Suppl 1), p.A147</ispartof><rights>2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Copyright: 2017 © 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids></links><search><creatorcontrib>Inostrosa, Marita Del Pilar Asmat</creatorcontrib><creatorcontrib>Valdazo, Javier Valdés</creatorcontrib><creatorcontrib>Robles, Jose Manuel De La Torre</creatorcontrib><creatorcontrib>Rio, Maria Victoria Casares Del</creatorcontrib><creatorcontrib>Herrero, Luis Enrrique Alonso</creatorcontrib><title>0463 Occupational intoxication by mercury and neurotoxicity: professional disease</title><title>Occupational and environmental medicine (London, England)</title><description>IntroductionMercury is a heavy metal found naturally in the environment. Mercury poisoning of occupational origin is widely identified as occupational disease. The industries where cases have been described are those dedicated to the manufacture of thermometers, barometers, as well as in gold mines and metal refineries such as zinc.MethodologyThe case of a 30-year-old male, a boilermaker (welder assembler) who is part of one of the teams responsible for replacing the carbon steel tubes of the exchanger through which sulphurous gases circulate with mercury remains is described. The initial symptoms were diarrhoea with mucus and blood and gum inflammation, initially presenting a blood mercury concentration of 475.9mcg/L (NV=<10 mcg/L) and urine mercury concentration 939mcg/L (NV=<30 Mcg/L) (BAL INSHT <5 mcg/g creatinine), not receiving treatment until after 6 months with DMPS twice seeing a reduction in urinary values from 1830.47 to 7.38 mcg/L. As a clinical result of mercury poisoning he had severe mercurial erethism with dysthymia and aggressive behaviour, as well as a secondary complex visual disorder and a diarrheal syndrome due to secondary autonomic neuropathy.ConclusionThis paper aims to warn about the consequences of prolonged exposure to mercury especially for the central nervous system, as well as early diagnosis and timely treatment. On the other hand, note the importance of adopting an adequate and effective preventive system to protect the health of workers exposed to mercury.</description><subject>2,3-Dimercapto-1-propanesulfonic acid</subject><subject>Aggressive behavior</subject><subject>Autonomic nervous system</subject><subject>Barometers</subject><subject>Blood</subject><subject>Blood levels</subject><subject>Boilers</subject><subject>Central nervous system</subject><subject>Creatinine</subject><subject>Diarrhea</subject><subject>Exposure</subject><subject>Gold</subject><subject>Heavy metals</subject><subject>Intoxication</subject><subject>Mercury</subject><subject>Mercury (metal)</subject><subject>Mucus</subject><subject>Neuropathy</subject><subject>Neurotoxicity</subject><subject>Occupational diseases</subject><subject>Occupational exposure</subject><subject>Occupational health</subject><subject>Poisoning</subject><subject>Refineries</subject><subject>Steel tubes</subject><subject>Thermometers</subject><subject>Urine</subject><subject>Zinc</subject><issn>1351-0711</issn><issn>1470-7926</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNotkE9LxDAQxYMouK5-BKHgOZrptEnrTRb_wcIe1HNI0il02bZr0oK9efGL-knMbj3NPOa94fFj7BrELQDKu55aqngqQHEQmUR5i0V2whaQKcFVmcrTuGMOXCiAc3YRwlYIQIXpgr0dAr_fPxvnxr0Zmr4zu6Tphv6rcUeZ2ClpybvRT4npqqSj0ffHczNM98ne9zWFMOeqJpAJdMnOarMLdPU_l-zj6fF99cLXm-fX1cOaWwCZ8TR1IkcS5KwjFwVYaZ2xCIWF1FZRk7C5RKXyqi5IqrpSCsuiLDPrshqX7Gb-G0t8jhQGve1HH4sEDSVGNCXkEF1idtl2q_e-aY2fNAh9QKeP6PQBnZ7R6YgO_wCd72SH</recordid><startdate>201708</startdate><enddate>201708</enddate><creator>Inostrosa, Marita Del Pilar Asmat</creator><creator>Valdazo, Javier Valdés</creator><creator>Robles, Jose Manuel De La Torre</creator><creator>Rio, Maria Victoria Casares Del</creator><creator>Herrero, Luis Enrrique Alonso</creator><general>BMJ Publishing Group LTD</general><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>L6V</scope><scope>M0S</scope><scope>M1P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope></search><sort><creationdate>201708</creationdate><title>0463 Occupational intoxication by mercury and neurotoxicity: professional disease</title><author>Inostrosa, Marita Del Pilar Asmat ; Valdazo, Javier Valdés ; Robles, Jose Manuel De La Torre ; Rio, Maria Victoria Casares Del ; Herrero, Luis Enrrique Alonso</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b1164-22c053e0ecbcec2c01b6bcab318b12bd01be0b563775df8e67fd77398994bc4f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>2,3-Dimercapto-1-propanesulfonic acid</topic><topic>Aggressive behavior</topic><topic>Autonomic nervous system</topic><topic>Barometers</topic><topic>Blood</topic><topic>Blood levels</topic><topic>Boilers</topic><topic>Central nervous system</topic><topic>Creatinine</topic><topic>Diarrhea</topic><topic>Exposure</topic><topic>Gold</topic><topic>Heavy metals</topic><topic>Intoxication</topic><topic>Mercury</topic><topic>Mercury (metal)</topic><topic>Mucus</topic><topic>Neuropathy</topic><topic>Neurotoxicity</topic><topic>Occupational diseases</topic><topic>Occupational exposure</topic><topic>Occupational health</topic><topic>Poisoning</topic><topic>Refineries</topic><topic>Steel tubes</topic><topic>Thermometers</topic><topic>Urine</topic><topic>Zinc</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Inostrosa, Marita Del Pilar Asmat</creatorcontrib><creatorcontrib>Valdazo, Javier Valdés</creatorcontrib><creatorcontrib>Robles, Jose Manuel De La Torre</creatorcontrib><creatorcontrib>Rio, Maria Victoria Casares Del</creatorcontrib><creatorcontrib>Herrero, Luis Enrrique Alonso</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Engineering Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><jtitle>Occupational and environmental medicine (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inostrosa, Marita Del Pilar Asmat</au><au>Valdazo, Javier Valdés</au><au>Robles, Jose Manuel De La Torre</au><au>Rio, Maria Victoria Casares Del</au><au>Herrero, Luis Enrrique Alonso</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>0463 Occupational intoxication by mercury and neurotoxicity: professional disease</atitle><jtitle>Occupational and environmental medicine (London, England)</jtitle><date>2017-08</date><risdate>2017</risdate><volume>74</volume><issue>Suppl 1</issue><spage>A147</spage><pages>A147-</pages><issn>1351-0711</issn><eissn>1470-7926</eissn><abstract>IntroductionMercury is a heavy metal found naturally in the environment. Mercury poisoning of occupational origin is widely identified as occupational disease. The industries where cases have been described are those dedicated to the manufacture of thermometers, barometers, as well as in gold mines and metal refineries such as zinc.MethodologyThe case of a 30-year-old male, a boilermaker (welder assembler) who is part of one of the teams responsible for replacing the carbon steel tubes of the exchanger through which sulphurous gases circulate with mercury remains is described. The initial symptoms were diarrhoea with mucus and blood and gum inflammation, initially presenting a blood mercury concentration of 475.9mcg/L (NV=<10 mcg/L) and urine mercury concentration 939mcg/L (NV=<30 Mcg/L) (BAL INSHT <5 mcg/g creatinine), not receiving treatment until after 6 months with DMPS twice seeing a reduction in urinary values from 1830.47 to 7.38 mcg/L. As a clinical result of mercury poisoning he had severe mercurial erethism with dysthymia and aggressive behaviour, as well as a secondary complex visual disorder and a diarrheal syndrome due to secondary autonomic neuropathy.ConclusionThis paper aims to warn about the consequences of prolonged exposure to mercury especially for the central nervous system, as well as early diagnosis and timely treatment. On the other hand, note the importance of adopting an adequate and effective preventive system to protect the health of workers exposed to mercury.</abstract><cop>London</cop><pub>BMJ Publishing Group LTD</pub><doi>10.1136/oemed-2017-104636.384</doi><oa>free_for_read</oa></addata></record> |
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| subjects | 2,3-Dimercapto-1-propanesulfonic acid Aggressive behavior Autonomic nervous system Barometers Blood Blood levels Boilers Central nervous system Creatinine Diarrhea Exposure Gold Heavy metals Intoxication Mercury Mercury (metal) Mucus Neuropathy Neurotoxicity Occupational diseases Occupational exposure Occupational health Poisoning Refineries Steel tubes Thermometers Urine Zinc |
| title | 0463 Occupational intoxication by mercury and neurotoxicity: professional disease |
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