The effects of chronic alcoholization on the expression of brain-derived neurotrophic factor and its receptors in the brains of mice genetically predisposed to depressive-like behavior

Brain-derived neurotropic factor (BDNF) plays an important role in mechanisms of depression. Precursor protein of this factor (proBDNF) can initiate apoptosis in the brain, while the mature form of BDNF is involved in neurogenesis. It is known that chronic alcoholization leads to the activation of a...

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Veröffentlicht in:	Molecular biology (New York) 2017-07, Vol.51 (4), p.571-578
Hauptverfasser:	Bazovkina, D. V., Kondaurova, E. M., Tsybko, A. S., Kovetskaya, A. I., Ilchibaeva, T. V., Naumenko, V. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biochemistry Biomedical and Life Sciences Brain Brain injury Brain-derived neurotrophic factor Cognitive ability Cortex (frontal) Ethanol Gene expression Hippocampus Human Genetics Life Sciences Mental depression Mice Molecular Cell Biology Neurodegeneration Neurogenesis p75 Protein Proteins Rodents TrkB receptors
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