Guideline for the prevention of acute chemotherapy‐induced nausea and vomiting in pediatric cancer patients: A focused update
This update of the 2013 clinical practice guideline provides clinicians with guidance regarding the use of aprepitant and palonosetron for the prevention of acute chemotherapy‐induced nausea and vomiting (CINV) in children. The recommendations were based on three systematic reviews. Substantive chan...
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Veröffentlicht in: | Pediatric blood & cancer 2017-10, Vol.64 (10), p.n/a |
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creator | Patel, Priya Robinson, Paula D. Thackray, Jennifer Flank, Jacqueline Holdsworth, Mark T. Gibson, Paul Orsey, Andrea Portwine, Carol Freedman, Jason Madden, Jennifer R. Phillips, Robert Sung, Lillian Dupuis, L. Lee |
description | This update of the 2013 clinical practice guideline provides clinicians with guidance regarding the use of aprepitant and palonosetron for the prevention of acute chemotherapy‐induced nausea and vomiting (CINV) in children. The recommendations were based on three systematic reviews. Substantive changes were made to the guideline recommendations including the inclusion of palonosetron to the 5‐HT3 antagonists recommended for children receiving highly emetogenic chemotherapy (HEC) and the recommendation of aprepitant for children 6 months of age or older receiving HEC. To optimize CINV control in children, future work must focus on closing critical research gaps. |
doi_str_mv | 10.1002/pbc.26542 |
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To optimize CINV control in children, future work must focus on closing critical research gaps.</description><identifier>ISSN: 1545-5009</identifier><identifier>EISSN: 1545-5017</identifier><identifier>DOI: 10.1002/pbc.26542</identifier><identifier>PMID: 28453189</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Adolescent ; Antagonists ; Cancer ; Chemotherapy ; Child ; Child, Preschool ; Children ; Female ; guideline ; Hematology ; Humans ; Infant ; Isoquinolines - therapeutic use ; Male ; Nausea ; Nausea - chemically induced ; Nausea - prevention & control ; Neoplasms - drug therapy ; Oncology ; Palonosetron ; Pediatrics ; Practice Guidelines as Topic ; Quinuclidines - therapeutic use ; Serotonin Antagonists - therapeutic use ; Serotonin S3 receptors ; supportive care ; Vomiting ; Vomiting - chemically induced ; Vomiting - prevention & control</subject><ispartof>Pediatric blood & cancer, 2017-10, Vol.64 (10), p.n/a</ispartof><rights>2017 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4542-3fdf3b567bd2d60fad203641523591b8aa811015277175af3b5d7845de01c5593</citedby><cites>FETCH-LOGICAL-c4542-3fdf3b567bd2d60fad203641523591b8aa811015277175af3b5d7845de01c5593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpbc.26542$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpbc.26542$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28453189$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patel, Priya</creatorcontrib><creatorcontrib>Robinson, Paula D.</creatorcontrib><creatorcontrib>Thackray, Jennifer</creatorcontrib><creatorcontrib>Flank, Jacqueline</creatorcontrib><creatorcontrib>Holdsworth, Mark T.</creatorcontrib><creatorcontrib>Gibson, Paul</creatorcontrib><creatorcontrib>Orsey, Andrea</creatorcontrib><creatorcontrib>Portwine, Carol</creatorcontrib><creatorcontrib>Freedman, Jason</creatorcontrib><creatorcontrib>Madden, Jennifer R.</creatorcontrib><creatorcontrib>Phillips, Robert</creatorcontrib><creatorcontrib>Sung, Lillian</creatorcontrib><creatorcontrib>Dupuis, L. Lee</creatorcontrib><title>Guideline for the prevention of acute chemotherapy‐induced nausea and vomiting in pediatric cancer patients: A focused update</title><title>Pediatric blood & cancer</title><addtitle>Pediatr Blood Cancer</addtitle><description>This update of the 2013 clinical practice guideline provides clinicians with guidance regarding the use of aprepitant and palonosetron for the prevention of acute chemotherapy‐induced nausea and vomiting (CINV) in children. The recommendations were based on three systematic reviews. Substantive changes were made to the guideline recommendations including the inclusion of palonosetron to the 5‐HT3 antagonists recommended for children receiving highly emetogenic chemotherapy (HEC) and the recommendation of aprepitant for children 6 months of age or older receiving HEC. To optimize CINV control in children, future work must focus on closing critical research gaps.</description><subject>Adolescent</subject><subject>Antagonists</subject><subject>Cancer</subject><subject>Chemotherapy</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Female</subject><subject>guideline</subject><subject>Hematology</subject><subject>Humans</subject><subject>Infant</subject><subject>Isoquinolines - therapeutic use</subject><subject>Male</subject><subject>Nausea</subject><subject>Nausea - chemically induced</subject><subject>Nausea - prevention & control</subject><subject>Neoplasms - drug therapy</subject><subject>Oncology</subject><subject>Palonosetron</subject><subject>Pediatrics</subject><subject>Practice Guidelines as Topic</subject><subject>Quinuclidines - therapeutic use</subject><subject>Serotonin Antagonists - therapeutic use</subject><subject>Serotonin S3 receptors</subject><subject>supportive care</subject><subject>Vomiting</subject><subject>Vomiting - chemically induced</subject><subject>Vomiting - prevention & control</subject><issn>1545-5009</issn><issn>1545-5017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kL9OwzAQhy0EoqUw8ALIEhNDWtuJ84etVFCQKsEAc-TYF-qqdYKdFHWCR-AZeRJcUrox-az77jvdD6FzSoaUEDaqCzlkMY_YAepTHvGAE5oc7muS9dCJcwuPxoSnx6jH0oiHNM366GPaagVLbQCXlcXNHHBtYQ2m0ZXBVYmFbBvAcg6ryjetqDffn1_aqFaCwka0DgQWRuF1tdKNNq9YG1yD0qKxWmIpjASLa9For3TXeOzXSD-kcFsr0cApOirF0sHZ7h2gl7vb58l9MHucPkzGs0BG_q4gLFUZFjxOCsVUTEqhGAnjiHIW8owWqRAppcR_k4QmXGxZlfgjFRAqOc_CAbrsvLWt3lpwTb6oWmv8ypxmIYkiRkjqqauOkrZyzkKZ11avhN3klOTbqHMfdf4btWcvdsa2WIHak3_ZemDUAe96CZv_TfnTzaRT_gCbbImU</recordid><startdate>201710</startdate><enddate>201710</enddate><creator>Patel, Priya</creator><creator>Robinson, Paula D.</creator><creator>Thackray, Jennifer</creator><creator>Flank, Jacqueline</creator><creator>Holdsworth, Mark T.</creator><creator>Gibson, Paul</creator><creator>Orsey, Andrea</creator><creator>Portwine, Carol</creator><creator>Freedman, Jason</creator><creator>Madden, Jennifer R.</creator><creator>Phillips, Robert</creator><creator>Sung, Lillian</creator><creator>Dupuis, L. 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subjects | Adolescent Antagonists Cancer Chemotherapy Child Child, Preschool Children Female guideline Hematology Humans Infant Isoquinolines - therapeutic use Male Nausea Nausea - chemically induced Nausea - prevention & control Neoplasms - drug therapy Oncology Palonosetron Pediatrics Practice Guidelines as Topic Quinuclidines - therapeutic use Serotonin Antagonists - therapeutic use Serotonin S3 receptors supportive care Vomiting Vomiting - chemically induced Vomiting - prevention & control |
title | Guideline for the prevention of acute chemotherapy‐induced nausea and vomiting in pediatric cancer patients: A focused update |
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