Guideline for the prevention of acute chemotherapy‐induced nausea and vomiting in pediatric cancer patients: A focused update

This update of the 2013 clinical practice guideline provides clinicians with guidance regarding the use of aprepitant and palonosetron for the prevention of acute chemotherapy‐induced nausea and vomiting (CINV) in children. The recommendations were based on three systematic reviews. Substantive chan...

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Veröffentlicht in:Pediatric blood & cancer 2017-10, Vol.64 (10), p.n/a
Hauptverfasser: Patel, Priya, Robinson, Paula D., Thackray, Jennifer, Flank, Jacqueline, Holdsworth, Mark T., Gibson, Paul, Orsey, Andrea, Portwine, Carol, Freedman, Jason, Madden, Jennifer R., Phillips, Robert, Sung, Lillian, Dupuis, L. Lee
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container_issue 10
container_start_page
container_title Pediatric blood & cancer
container_volume 64
creator Patel, Priya
Robinson, Paula D.
Thackray, Jennifer
Flank, Jacqueline
Holdsworth, Mark T.
Gibson, Paul
Orsey, Andrea
Portwine, Carol
Freedman, Jason
Madden, Jennifer R.
Phillips, Robert
Sung, Lillian
Dupuis, L. Lee
description This update of the 2013 clinical practice guideline provides clinicians with guidance regarding the use of aprepitant and palonosetron for the prevention of acute chemotherapy‐induced nausea and vomiting (CINV) in children. The recommendations were based on three systematic reviews. Substantive changes were made to the guideline recommendations including the inclusion of palonosetron to the 5‐HT3 antagonists recommended for children receiving highly emetogenic chemotherapy (HEC) and the recommendation of aprepitant for children 6 months of age or older receiving HEC. To optimize CINV control in children, future work must focus on closing critical research gaps.
doi_str_mv 10.1002/pbc.26542
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subjects Adolescent
Antagonists
Cancer
Chemotherapy
Child
Child, Preschool
Children
Female
guideline
Hematology
Humans
Infant
Isoquinolines - therapeutic use
Male
Nausea
Nausea - chemically induced
Nausea - prevention & control
Neoplasms - drug therapy
Oncology
Palonosetron
Pediatrics
Practice Guidelines as Topic
Quinuclidines - therapeutic use
Serotonin Antagonists - therapeutic use
Serotonin S3 receptors
supportive care
Vomiting
Vomiting - chemically induced
Vomiting - prevention & control
title Guideline for the prevention of acute chemotherapy‐induced nausea and vomiting in pediatric cancer patients: A focused update
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