Anti‐Inflammatory and Antioxidant Actions of Copaiba Oil Are Related to Liver Cell Modifications in Arthritic Rats

ABSTRACT The present study investigated the action of copaiba oil (Copaifera reticulata) on the systemic inflammation, oxidative status, and liver cell metabolism of rats with adjuvant‐induced arthritis. The later is an experimental autoimmune pathology that shares many features with the human rheum...

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Veröffentlicht in:	Journal of cellular biochemistry 2017-10, Vol.118 (10), p.3409-3423
Hauptverfasser:	Castro Ghizoni, Cristiane V., Arssufi Ames, Ana P., Lameira, Osmar A., Bersani Amado, Ciomar A., Sá Nakanishi, Anacharis B., Bracht, Lívia, Marçal Natali, Maria R., Peralta, Rosane M., Bracht, Adelar, Comar, Jurandir F.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADJUVANT‐INDUCED ARTHRITIS Animals Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacokinetics Anti-Inflammatory Agents - pharmacology Antioxidants Antioxidants - chemistry Antioxidants - pharmacokinetics Antioxidants - pharmacology Arthritis Arthritis, Experimental - drug therapy Arthritis, Experimental - metabolism Arthritis, Experimental - pathology Body weight Body weight gain Carbonyl compounds Carbonyl groups Carbonyls Catalase COPAIBA OIL COPAIFERA RETICULATA Cytology Edema Fabaceae - chemistry Gluconeogenesis Glycolysis Hepatocytes Inflammation Liver Liver - pathology LIVER METABOLISM LIVER TOXICITY Lymph nodes Male Metabolism OXIDATIVE STATUS Peroxidase Plant Oils - chemistry Plant Oils - pharmacokinetics Plant Oils - pharmacology Rats Rats, Sprague-Dawley Reactive oxygen species Rheumatoid arthritis Rodent control Rodents
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