A27 BRONCHIECTASIS AND LUNG INFECTION: Detection Of Previously Missed Pathogens In Immunocompromised Children With Pneumonia by A Fully-Validated Next-Generation Sequencing Test

Banked BAL samples from children with leukemia, solid organ or hematopoietic stem cell transplant, severe combined immunodeficiency and/or prolonged high dose steroid therapy were included based on radiographic and clinical evidence of pneumonia and extensive, broad, unrevealing diagnostic workup. B...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Schlaberg, R, Xie, H, Flygare, S, Mei, Y, Matsuzaki, H, Yandell, M, Graf, E H
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title American journal of respiratory and critical care medicine
container_volume 195
creator Schlaberg, R
Xie, H
Flygare, S
Mei, Y
Matsuzaki, H
Yandell, M
Graf, E H
description Banked BAL samples from children with leukemia, solid organ or hematopoietic stem cell transplant, severe combined immunodeficiency and/or prolonged high dose steroid therapy were included based on radiographic and clinical evidence of pneumonia and extensive, broad, unrevealing diagnostic workup. Bacterial pathogens were detected in 13, fungal pathogens in 7, and viral pathogens in 3 patients (Figure).
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_journals_1926868858</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1926868858</sourcerecordid><originalsourceid>FETCH-proquest_journals_19268688583</originalsourceid><addsrcrecordid>eNqNjdtOg0AURYnRxHr5h5P4TMK1gG9IS0uiQyN4eWtGOC3TDDPKDI18ln_oaPwAn_bOXivZJ9bMDf3QDpLIOTXdiXw7CJLXc-tCqYPjuF7sOjPrK_UiuHssSbYullmdVkUFKVnA_RNZQUFysxUluYUFamw0kwLKHWwGPDI5Kj7BA1MKW9hQ3ck9CgWFgKLvRyEb2b8Psmc_OOsYbwcU8MJ0BxuBYy8Fo_A2QQr5yPlkP1POWqqNTPBT2ysUONDfwwo_RhQNE3uoUekr62xHucLrv7y0bvJlna1t82ZEpbcHOQ7CoK2bePN4Hsdh7P_P-gZt_GB_</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1926868858</pqid></control><display><type>article</type><title>A27 BRONCHIECTASIS AND LUNG INFECTION: Detection Of Previously Missed Pathogens In Immunocompromised Children With Pneumonia by A Fully-Validated Next-Generation Sequencing Test</title><source>Journals@Ovid Complete</source><source>American Thoracic Society (ATS) Journals Online</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Schlaberg, R ; Xie, H ; Flygare, S ; Mei, Y ; Matsuzaki, H ; Yandell, M ; Graf, E H</creator><creatorcontrib>Schlaberg, R ; Xie, H ; Flygare, S ; Mei, Y ; Matsuzaki, H ; Yandell, M ; Graf, E H</creatorcontrib><description>Banked BAL samples from children with leukemia, solid organ or hematopoietic stem cell transplant, severe combined immunodeficiency and/or prolonged high dose steroid therapy were included based on radiographic and clinical evidence of pneumonia and extensive, broad, unrevealing diagnostic workup. Bacterial pathogens were detected in 13, fungal pathogens in 7, and viral pathogens in 3 patients (Figure).</description><identifier>ISSN: 1073-449X</identifier><identifier>EISSN: 1535-4970</identifier><language>eng</language><publisher>New York: American Thoracic Society</publisher><subject>Laboratories ; Pathogens ; Pneumonia ; Stem cell transplantation</subject><ispartof>American journal of respiratory and critical care medicine, 2017-01, Vol.195</ispartof><rights>Copyright American Thoracic Society 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Schlaberg, R</creatorcontrib><creatorcontrib>Xie, H</creatorcontrib><creatorcontrib>Flygare, S</creatorcontrib><creatorcontrib>Mei, Y</creatorcontrib><creatorcontrib>Matsuzaki, H</creatorcontrib><creatorcontrib>Yandell, M</creatorcontrib><creatorcontrib>Graf, E H</creatorcontrib><title>A27 BRONCHIECTASIS AND LUNG INFECTION: Detection Of Previously Missed Pathogens In Immunocompromised Children With Pneumonia by A Fully-Validated Next-Generation Sequencing Test</title><title>American journal of respiratory and critical care medicine</title><description>Banked BAL samples from children with leukemia, solid organ or hematopoietic stem cell transplant, severe combined immunodeficiency and/or prolonged high dose steroid therapy were included based on radiographic and clinical evidence of pneumonia and extensive, broad, unrevealing diagnostic workup. Bacterial pathogens were detected in 13, fungal pathogens in 7, and viral pathogens in 3 patients (Figure).</description><subject>Laboratories</subject><subject>Pathogens</subject><subject>Pneumonia</subject><subject>Stem cell transplantation</subject><issn>1073-449X</issn><issn>1535-4970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNjdtOg0AURYnRxHr5h5P4TMK1gG9IS0uiQyN4eWtGOC3TDDPKDI18ln_oaPwAn_bOXivZJ9bMDf3QDpLIOTXdiXw7CJLXc-tCqYPjuF7sOjPrK_UiuHssSbYullmdVkUFKVnA_RNZQUFysxUluYUFamw0kwLKHWwGPDI5Kj7BA1MKW9hQ3ck9CgWFgKLvRyEb2b8Psmc_OOsYbwcU8MJ0BxuBYy8Fo_A2QQr5yPlkP1POWqqNTPBT2ysUONDfwwo_RhQNE3uoUekr62xHucLrv7y0bvJlna1t82ZEpbcHOQ7CoK2bePN4Hsdh7P_P-gZt_GB_</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Schlaberg, R</creator><creator>Xie, H</creator><creator>Flygare, S</creator><creator>Mei, Y</creator><creator>Matsuzaki, H</creator><creator>Yandell, M</creator><creator>Graf, E H</creator><general>American Thoracic Society</general><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20170101</creationdate><title>A27 BRONCHIECTASIS AND LUNG INFECTION: Detection Of Previously Missed Pathogens In Immunocompromised Children With Pneumonia by A Fully-Validated Next-Generation Sequencing Test</title><author>Schlaberg, R ; Xie, H ; Flygare, S ; Mei, Y ; Matsuzaki, H ; Yandell, M ; Graf, E H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_19268688583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Laboratories</topic><topic>Pathogens</topic><topic>Pneumonia</topic><topic>Stem cell transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schlaberg, R</creatorcontrib><creatorcontrib>Xie, H</creatorcontrib><creatorcontrib>Flygare, S</creatorcontrib><creatorcontrib>Mei, Y</creatorcontrib><creatorcontrib>Matsuzaki, H</creatorcontrib><creatorcontrib>Yandell, M</creatorcontrib><creatorcontrib>Graf, E H</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>American journal of respiratory and critical care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schlaberg, R</au><au>Xie, H</au><au>Flygare, S</au><au>Mei, Y</au><au>Matsuzaki, H</au><au>Yandell, M</au><au>Graf, E H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A27 BRONCHIECTASIS AND LUNG INFECTION: Detection Of Previously Missed Pathogens In Immunocompromised Children With Pneumonia by A Fully-Validated Next-Generation Sequencing Test</atitle><jtitle>American journal of respiratory and critical care medicine</jtitle><date>2017-01-01</date><risdate>2017</risdate><volume>195</volume><issn>1073-449X</issn><eissn>1535-4970</eissn><abstract>Banked BAL samples from children with leukemia, solid organ or hematopoietic stem cell transplant, severe combined immunodeficiency and/or prolonged high dose steroid therapy were included based on radiographic and clinical evidence of pneumonia and extensive, broad, unrevealing diagnostic workup. Bacterial pathogens were detected in 13, fungal pathogens in 7, and viral pathogens in 3 patients (Figure).</abstract><cop>New York</cop><pub>American Thoracic Society</pub></addata></record>
fulltext fulltext
identifier ISSN: 1073-449X
ispartof American journal of respiratory and critical care medicine, 2017-01, Vol.195
issn 1073-449X
1535-4970
language eng
recordid cdi_proquest_journals_1926868858
source Journals@Ovid Complete; American Thoracic Society (ATS) Journals Online; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Laboratories
Pathogens
Pneumonia
Stem cell transplantation
title A27 BRONCHIECTASIS AND LUNG INFECTION: Detection Of Previously Missed Pathogens In Immunocompromised Children With Pneumonia by A Fully-Validated Next-Generation Sequencing Test
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T06%3A18%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A27%20BRONCHIECTASIS%20AND%20LUNG%20INFECTION:%20Detection%20Of%20Previously%20Missed%20Pathogens%20In%20Immunocompromised%20Children%20With%20Pneumonia%20by%20A%20Fully-Validated%20Next-Generation%20Sequencing%20Test&rft.jtitle=American%20journal%20of%20respiratory%20and%20critical%20care%20medicine&rft.au=Schlaberg,%20R&rft.date=2017-01-01&rft.volume=195&rft.issn=1073-449X&rft.eissn=1535-4970&rft_id=info:doi/&rft_dat=%3Cproquest%3E1926868858%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1926868858&rft_id=info:pmid/&rfr_iscdi=true