C73 NEW MECHANISMS AND THERAPIES IN COPD: Simple Prediction Of Mmp-9/timp-1 Ratio Derived From One Of Biomarkers (the Study Is Limited To The Examination Of Mmp-9 And Timp-1 From The Saliva Among Ex-Smokers With Chronic Obstructive Pulmonary Disease)

Corresponding author's email: mul.0862@gmail.com Emphysemais commonly found among ex-smokers experienced chronic obstructive pulmonary disease (COPD) with clinically manifest of irreversible shortness of breath. Thisrefers tothe damaged lung parenchyma tissue and the extracellular matrix characterized by the increase of MMP-9 biomarker and the ratio of MMP-9 / TIMP-1 from the sputum and lung lavage fluid.