C74 ADVANCES IN TRANSLATIONAL COPD: Role Of Sphingomyelin Synthase Regulated Micro Domain Signaling In Cigarette Smoke Induced Inflammation

Recent studies from our laboratory have shown that sphingomyelin synthase-2 (SMS2) activation-dependent conversion of ceramide (Cer) to SM is critical in regulating the cigarette smoke (CS) as well as endotoxin induced inflammatory response. Furthermore, we found that SMS2 in the lipid raft microdom...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser:	Wadgaonkar, R, Geraghty, P, Kabir, I, onjy, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic obstructive pulmonary disease Lipids Rodents
Online-Zugang:	Volltext
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