Hepatoprotective activity of different extracts of Pterospermum acerifolium against paracetamol induced hepatotoxicity in albino rats

Hepatoprotective activity of different extracts of Pterospermum acerifolium against paracetamol induced hepatotoxicity in albino rats

The petroleum ether and hydro alcoholic extracts of Pterospermum acerifolium belonging to the Sterculiaceae family were studied for hepatoprotective activity against albino rats with liver damage induced by paracetamol. The petroleum ether extract at 50 mg/kg was having best activity as it decreased...

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Veröffentlicht in:The pharma innovation 2016-03, Vol.5 (3, Part A), p.32
Hauptverfasser: Mathew, George, Lincy, Joseph, Deshwal, Neetu, Jeenu, Joseph
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Albinism
Analgesics
Herbs
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description The petroleum ether and hydro alcoholic extracts of Pterospermum acerifolium belonging to the Sterculiaceae family were studied for hepatoprotective activity against albino rats with liver damage induced by paracetamol. The petroleum ether extract at 50 mg/kg was having best activity as it decreased the mean level of bilirubin from 2.3645 ± 0.07 to 0.2975 ± 0.13. Petroleum ether extract was found to highly protective at both the dose of 25 mg/kg and 50 mg/kg for ALP, SGOT, and SGPT. For LPO level, SOD and Catalase level it was observed that both extract were having significantly protection at 25 mg/kg and 50 mg/kg dose.
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subjects Albinism
Analgesics
Herbs
title Hepatoprotective activity of different extracts of Pterospermum acerifolium against paracetamol induced hepatotoxicity in albino rats
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