Can we predict protein from mRNA levels?/Wilhelm et al. reply

Prediction of protein levels from mRNA levels has long been fraught with unreliability and a lack of precision. However, Wilhelm et al.1 claimed that using estimated gene-specific translation rates together with mRNA levels accurately predicts protein levels in any given tissue, reporting correlatio...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nature (London) 2017-07, Vol.547 (7664), p.E19
Hauptverfasser:	telny, Nikolaus, Overall, Christopher M, Pavlidis, Paul, Freue, Gabriela V Cohen, Wilhelm, Mathias, Hahne, Hannes, Savitski, Mikhail, Marx, Harald, Lemeer, Simone, Bantscheff, Marcus, Kuster, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Genes mRNA Proteins Ribonucleic acid RNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!