Three‐Component Coupling Reaction in Water: A One‐Pot Protocol for the Construction of P–S–C(sp3) and P–Se–C(sp3) Bonds

A one‐pot, three‐component coupling reaction of primary alkyl halides (or tosylates), elemental sulfur/selenium, and P(O)–H compounds in water was developed. This procedure affords valuable phosphorothioates/phosphoroselenoates, including P‐chiral compounds, with broad substrate scope and high effic...

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Veröffentlicht in:European journal of organic chemistry 2017-04, Vol.2017 (14), p.1884-1888
Hauptverfasser: Zhang, Xinghua, Shi, Zheng, Shao, Changwei, Zhao, Jinlong, Wang, Dungai, Zhang, Gaoqi, Li, Liang
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Sprache:eng
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