Amplified detection of leukemia cancer cells using an aptamer-conjugated gold-coated magnetic nanoparticles on a nitrogen-doped graphene modified electrode

The increasing demands for early, accurate and ultrasensitive diagnosis of cancers demonstrate the importance of the development of new amplification strategies or diagnostic technologies. In the present study, an aptamer-based electrochemical biosensor for ultrasensitive and selective detection of...

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Veröffentlicht in:	Bioelectrochemistry (Amsterdam, Netherlands) Netherlands), 2017-04, Vol.114, p.24-32
Hauptverfasser:	Khoshfetrat, Seyyed Mehdi, Mehrgardi, Masoud A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Aptamer Aptamers Aptamers, Nucleotide - genetics Aptamers, Nucleotide - metabolism Base Sequence Biosensing Techniques - instrumentation Biosensing Techniques - methods Blood plasma Cancer Cancer cell CCRF-CEM Cell Line, Tumor Coated electrodes Complex media Diagnostic systems Dynamic range Electrochemistry Electrodes Ethidium bromide Gold Gold - chemistry Gold coated magnetic nanoparticle Graphene Graphite - chemistry Humans Hydrogen-Ion Concentration Immobilization Iron oxides Leukemia Leukemia - pathology Magnetite Nanoparticles - chemistry Metal Nanoparticles - chemistry Nanoparticles Nitrogen - chemistry Nitrogen-doped graphene Time Factors
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