MALAKOPLAKIA OF APPENDIX: A CASE REPORT

Colonoscopy was done and showed irregular, erythematous, friable mass in the appendicular orifice, from which multiple biopsies were taken and sent to Armed Forces Institute of Pathology (AFIP) for histopathological examination. Special stains including Periodic acid Schiff (PAS) with diastase, Perl's stain, von Kossa stain were applied which highlighted MG bodies (fig-1b,c,d,e). The most common site of involvement is urinary bladder and rarely it involves pelvis of the kidney, ureter, urethra, stomach, small and large intestines, appendix, anal canal, perianal region, retroperitoneum, adrenal gland, prostate, epididymis, cervix, vagina, skin, breast, muscle, lymph nodes, bone and brain. The lesion evolves through 3 phases: an early phase, in which MG bodies are not seen but plasma cells and histiocytes are present in the edematous stroma; a classic phase, in which MG bodies are present in histiocytes alongwith few lymphocytes and plasma cells; and a fibrosing phase, in which occasional MG bodies are present in histiocytes among fibroblasts and collagen in well-defined bundles2. Partially digested bacteria with iron and calcium phosphate are present in the central zone. Correspondence: Dr Syed Salman Ali, House No 16 Lane 27 Phase-II Wah Model Town Wah Cantt Pakistan Email: syedsalmanali85@gmail.com Received: 22 Nov 2016; revised received: 20...