Silver‐Catalyzed Direct C6–H Arylation of Purines and Purine Nucleosides with Arylboronic Acids

A practical and operationally simple protocol for the assembly of 6‐aryl‐substituted purines through the direct C6–H arylation of purines and 8‐azapurine and purine nucleosides from arylboronic acids was developed. This reaction was performed under ambient conditions with ammonium persulfate as the...

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Veröffentlicht in:	European journal of organic chemistry 2017-06, Vol.2017 (24), p.3415-3420
Hauptverfasser:	Tian, Miao, Yu, Mingwu, Shi, Tingting, Hu, Junbin, Li, Shunlai, Xu, Jiaxi, Chen, Ning, Du, Hongguang
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonium peroxodisulfate Aromatic compounds Assembly Boronic acids C–H activation Esters Functional groups Halides Nucleosides Purines Silver
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