Acute Naproxen Dose on Hydration and Electrolyte Measures During Moderate-Intense Exercise in the Heat

An abstract of a study by Emerson et al determining acute dose effects of a commonly used over the counter non-steroidal anti-inflammatory drugs, naproxen, on fluid and electrolyte measures during moderate-intense endurance exercise in a hot or ambient environment is presented. Results show no stati...

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Veröffentlicht in:Journal of athletic training 2017-06, Vol.52 (6), p.S51
Hauptverfasser: Emerson, D M, Torres-McGehee, T M, Davis, J M, Chen, S C L, Durstine, J L, Pfeifer, C E, Emerson, C C, Stone, J V, Bivona, J D
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container_issue 6
container_start_page S51
container_title Journal of athletic training
container_volume 52
creator Emerson, D M
Torres-McGehee, T M
Davis, J M
Chen, S C L
Durstine, J L
Pfeifer, C E
Emerson, C C
Stone, J V
Bivona, J D
description An abstract of a study by Emerson et al determining acute dose effects of a commonly used over the counter non-steroidal anti-inflammatory drugs, naproxen, on fluid and electrolyte measures during moderate-intense endurance exercise in a hot or ambient environment is presented. Results show no statistically significant differences between experimental trials for hydration, electrolyte, or cardiovascular measures. All participants began data collection euhydrated (mean Posm = 286 + 6.4 mOsm/L) and maintained hydration throughout exercise and rest. Mean aggregate plasma sodium (PNa) was < 135 mmol/L at pre, post-, and 3 hours post-exercise and did not significantly change over time. Aggregate plasma potassium concentration (PK) significantly increased pre- to post-exercise (3.9 + 0.4 to 4.2 + 0.4 mmol/L, P = 0.02). Compared to placebo trials, naproxen trials at post-exercise had higher PK, lower PNa, and lower Posm. Similarly, mean Fvol during exercise and total was higher and Uvol was lower in naproxen trials compared to placebo trials.
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Results show no statistically significant differences between experimental trials for hydration, electrolyte, or cardiovascular measures. All participants began data collection euhydrated (mean Posm = 286 + 6.4 mOsm/L) and maintained hydration throughout exercise and rest. Mean aggregate plasma sodium (PNa) was &lt; 135 mmol/L at pre, post-, and 3 hours post-exercise and did not significantly change over time. Aggregate plasma potassium concentration (PK) significantly increased pre- to post-exercise (3.9 + 0.4 to 4.2 + 0.4 mmol/L, P = 0.02). Compared to placebo trials, naproxen trials at post-exercise had higher PK, lower PNa, and lower Posm. 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subjects Body Composition
Climate
Electrolytes
Environment
Heat
Humidity
Hydration
Laboratories
Outcome Measures
Scientific Concepts
Urine
title Acute Naproxen Dose on Hydration and Electrolyte Measures During Moderate-Intense Exercise in the Heat
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