Possible Changes of Pharmacokinetics of IL-2 Deposited in Red Blood Cells (RBC)

Possible Changes of Pharmacokinetics of IL-2 Deposited in Red Blood Cells (RBC)

Received data on concentration of IL- 2 level in blood serum after intravenous administration of drug with and without deposition to the suspension of blood cells were approximated within the frame of compartmental two-chambered pharmacokinetic model: Increased volume in the central chamber (blood),...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical therapeutics 2017-08, Vol.39 (8), p.e79-e79
Hauptverfasser: Tritek, V, Zhaugasheva, S.K, Gulyayev, A, Sergazy, Sh, Khassenbekova, Zh, Yermekbayeva, B, Nurgozhin, T
Format: Artikel
Sprache:eng
Schlagworte:
Blood
Cytokines
Erythrocytes
Interleukin 2
Internal Medicine
Intravenous administration
Medical Education
Pharmacokinetics
Pharmacology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Received data on concentration of IL- 2 level in blood serum after intravenous administration of drug with and without deposition to the suspension of blood cells were approximated within the frame of compartmental two-chambered pharmacokinetic model: Increased volume in the central chamber (blood), and increased amounts of kinetic and stationary...
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2017.05.244