Fipronil-induced genotoxicity and DNA damage in vivo: Protective effect of vitamin E

Fipronil, an insecticide of the phenylpyrazole class has been classified as a carcinogen by United States Environmental Protection Agency, yet very limited information is available about its genotoxic effects. Adult male and female animals were gavaged with various doses of fipronil (2.5, 12.5, and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human & experimental toxicology 2017-05, Vol.36 (5), p.508-519
Hauptverfasser:	Badgujar, PC, Selkar, NA, Chandratre, GA, Pawar, NN, Dighe, VD, Bhagat, ST, Telang, AG, Vanage, GR
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Animals Antiparasitic Agents - toxicity Assaying Bioassays Body weight Bone marrow Bone Marrow Cells - drug effects Carcinogens Comet Assay Cyclophosphamide Damage detection Deoxyribonucleic acid DNA DNA Damage Environmental protection Erythrocytes Exposure Female Fipronil Gender Genotoxicity In vivo methods and tests Insecticides - toxicity Lymphocytes Lymphocytes - drug effects Male Mice Micronuclei Micronuclei, Chromosome-Defective - chemically induced Micronucleus Tests Pesticides Phenylpyrazole Pretreatment Protective Agents - pharmacology Pyrazoles - toxicity Rats Rats, Sprague-Dawley Rodents Structural damage Tocopherol Toxicity Vitamin E Vitamin E - pharmacology Vitamins - pharmacology
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!