How to Diagnosis the Occult Hepatitis C Virus?

How to Diagnosis the Occult Hepatitis C Virus?

Occult hepatitis C (OHC) virus infection, defined as the presence of hepatitis C virus (HCV) RNA in the liver and in peripheral blood mononuclear cells (PBMCs) in the absence of detectable viral RNA in serum, can be found in anti-HCV positive patients with normal serum levels of liver enzymes and in...

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Veröffentlicht in:Viral Hepatit Dergisi 2017-04, Vol.23 (1), p.37-38
Hauptverfasser: ASLAN, Ferhat Gürkan, ALTINDİŞ, Mustafa
Format: Artikel
Sprache:eng
Schlagworte:
Acids
Enzymes
Hemodialysis
Hepatitis
Hepatitis C
Infections
Interferon
Liver
Medical diagnosis
Tıp
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ALTINDİŞ, Mustafa
description Occult hepatitis C (OHC) virus infection, defined as the presence of hepatitis C virus (HCV) RNA in the liver and in peripheral blood mononuclear cells (PBMCs) in the absence of detectable viral RNA in serum, can be found in anti-HCV positive patients with normal serum levels of liver enzymes and in anti-HCV negative patients with persistently elevated liver enzymes of unknown etiology. OHC has been described using highly sensitive nucleic acid amplification assays with a sensitivity of
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OHC has been described using highly sensitive nucleic acid amplification assays with a sensitivity of &lt;3 IU/mL. Different studies have revealed that HCV RNA can persist and replicate in immune cells but the relevance of its presence and persistence over time is still unknown. 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ispartof Viral Hepatit Dergisi, 2017-04, Vol.23 (1), p.37-38
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language eng
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source Alma/SFX Local Collection
subjects Acids
Enzymes
Hemodialysis
Hepatitis
Hepatitis C
Infections
Interferon
Liver
Medical diagnosis
Tıp
title How to Diagnosis the Occult Hepatitis C Virus?
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