Back Cover: Ternary Hybrid [gamma]-Fe2O3/CrVI/Amine Oxidase Nanostructure for Electrochemical Sensing: Application for Polyamine Detection in Tumor Tissue

Polyamine detector: Dichromate binds to surface-active maghemite nanoparticles (SAMN) to form a stable core-shell nanostructure (SAMN@CrVI), which is an excellent electrocatalyst for hydrogen peroxide reduction. Bovine serum amine oxidase was immobilized on SAMN@CrVI to give a ternary hybrid nanostr...

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Veröffentlicht in:Chemistry : a European journal 2016-05, Vol.22 (20), p.6988
Hauptverfasser: Bonaiuto, Emanuela, Magro, Massimiliano, Baratella, Davide, Jakubec, Petr, Sconcerle, Elisabetta, Terzo, Milo, Miotto, Giovanni, Macone, Alberto, Agostinelli, Enzo, Fasolato, Silvano, Venerando, Rina, Salviulo, Gabriella, Malina, Ondrej, Zboril, Radek, Vianello, Fabio
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Sprache:eng
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Zusammenfassung:Polyamine detector: Dichromate binds to surface-active maghemite nanoparticles (SAMN) to form a stable core-shell nanostructure (SAMN@CrVI), which is an excellent electrocatalyst for hydrogen peroxide reduction. Bovine serum amine oxidase was immobilized on SAMN@CrVI to give a ternary hybrid nanostructured catalyst for polyamine oxidation, which was used to develop a reagentless, fast, inexpensive, and interference-free polyamine biosensor for the discrimination of tumor tissue from healthy tissue in human crude liver extracts (see figure). More information can be found in the Full Paper by F. Vianello et al. on page6846ff.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201601077