Skin nerve misfolded [alpha]-synuclein in pure autonomic failure and Parkinson disease

Objective To characterize the expression in skin nerves of native (n-syn) and misfolded phosphorylated (p-syn) [alpha]-synucleins in pure autonomic failure (PAF) and idiopathic Parkinson disease (IPD). The specific aims were to (1) define the importance of n-syn and p-syn as disease biomarkers and (...

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